1 00:00:01,333 --> 00:00:05,150 Computer algorithms today are performing incredible tasks 2 00:00:05,174 --> 00:00:09,682 with high accuracies, at a massive scale, using human-like intelligence. 3 00:00:10,053 --> 00:00:13,863 And this intelligence of computers is often referred to as AI 4 00:00:13,887 --> 00:00:15,736 or artificial intelligence. 5 00:00:15,760 --> 00:00:20,427 AI is poised to make an incredible impact on our lives in the future. 6 00:00:20,911 --> 00:00:24,807 Today, however, we still face massive challenges 7 00:00:24,831 --> 00:00:28,325 in detecting and diagnosing several life-threatening illnesses, 8 00:00:28,349 --> 00:00:30,854 such as infectious diseases and cancer. 9 00:00:32,023 --> 00:00:34,277 Thousands of patients, every year, 10 00:00:34,301 --> 00:00:37,434 lose their lives due to liver and oral cancer. 11 00:00:37,894 --> 00:00:40,577 Our best way to help these patients 12 00:00:40,601 --> 00:00:44,910 is to perform early detection and diagnoses of these diseases. 13 00:00:45,871 --> 00:00:50,260 So how do we detect these diseases today and can artificial intelligence help? 14 00:00:51,966 --> 00:00:55,592 In patients who, unfortunately, are suspected of these diseases, 15 00:00:55,616 --> 00:00:58,243 an expert physician first orders 16 00:00:58,267 --> 00:01:00,893 very expensive medical imaging technologies 17 00:01:00,917 --> 00:01:04,668 such as fluorescent imaging, CTs, MRIs, to be performed. 18 00:01:05,046 --> 00:01:07,339 Once those images are collected, 19 00:01:07,363 --> 00:01:12,107 another expert physician then diagnoses those images and talks to the patient. 20 00:01:12,522 --> 00:01:15,958 As you can see, this is a very resource-intensive process, 21 00:01:15,982 --> 00:01:20,418 requiring both expert physicians, expensive medical imaging technologies, 22 00:01:20,442 --> 00:01:23,521 and is not considered practical for the developing world. 23 00:01:23,545 --> 00:01:27,037 And in fact, in many industrialized nations, as well. 24 00:01:27,784 --> 00:01:31,069 So, can we solve this problem using artificial intelligence? 25 00:01:31,887 --> 00:01:35,903 Today, if I were to use traditional artificial intelligence architectures 26 00:01:35,927 --> 00:01:37,133 to solve this problem, 27 00:01:37,157 --> 00:01:38,736 I would require 10,000 -- 28 00:01:38,760 --> 00:01:42,664 I repeat, on an order of 10,000 of these very expensive medical images 29 00:01:42,688 --> 00:01:44,085 first to be generated. 30 00:01:44,109 --> 00:01:46,974 After that, I would then go to an expert physician, 31 00:01:46,998 --> 00:01:49,514 who would then analyze those images for me. 32 00:01:49,538 --> 00:01:51,696 And using those two pieces of information, 33 00:01:51,720 --> 00:01:55,299 I can train a standard deep neural network or a deep learning network, 34 00:01:55,323 --> 00:01:57,459 to provide patient's diagnosis. 35 00:01:57,483 --> 00:01:59,198 Similar to the first approach, 36 00:01:59,222 --> 00:02:01,388 traditional artificial intelligence approaches 37 00:02:01,412 --> 00:02:02,856 suffer from the same problem. 38 00:02:02,880 --> 00:02:07,322 Large amounts of data, expert physicians, and expert medical imaging technologies. 39 00:02:08,354 --> 00:02:12,601 So can we invent more scalable, effective, 40 00:02:12,625 --> 00:02:15,934 and more valuable artificial intelligence architectures 41 00:02:15,958 --> 00:02:18,692 to solve these very important problems facing us today? 42 00:02:19,034 --> 00:02:22,049 And this is exactly what my group at MIT Media Lab does. 43 00:02:22,375 --> 00:02:26,200 We have invented a variety of unorthodox AI architectures 44 00:02:26,224 --> 00:02:29,426 to solve some of the most important challenges facing us today 45 00:02:29,450 --> 00:02:31,902 in medical imaging and clinical trials. 46 00:02:32,482 --> 00:02:35,537 In the example I shared with you today, we had two goals. 47 00:02:35,561 --> 00:02:38,522 Our first goal was to reduce the number of images 48 00:02:38,546 --> 00:02:41,815 required to train artificial intelligence algorithms. 49 00:02:41,839 --> 00:02:43,926 Our second goal -- we were more ambitious, 50 00:02:43,950 --> 00:02:47,712 we wanted to reduce the use of expensive medical imaging technologies 51 00:02:47,736 --> 00:02:48,934 to screen patients. 52 00:02:48,958 --> 00:02:50,292 So how did we do it? 53 00:02:50,966 --> 00:02:52,149 For our first goal, 54 00:02:52,173 --> 00:02:54,220 instead of starting with tens and thousands 55 00:02:54,244 --> 00:02:57,253 of these very expensive medical images, like traditional AI, 56 00:02:57,277 --> 00:02:59,355 we started with a single medical image. 57 00:02:59,379 --> 00:03:03,125 From this image, my team and I figured out a very clever way 58 00:03:03,149 --> 00:03:05,895 to extract billions of information packets. 59 00:03:05,919 --> 00:03:09,628 These information packets included colors, pixels, geometry 60 00:03:09,652 --> 00:03:12,180 and rendering of the disease on the medical image. 61 00:03:12,204 --> 00:03:16,537 In a sense, we converted one image into billions of training data points, 62 00:03:16,561 --> 00:03:19,544 massively reducing the amount of data needed for training. 63 00:03:20,148 --> 00:03:21,323 For our second goal, 64 00:03:21,347 --> 00:03:25,220 to reduce the use of expensive medical imaging technologies to screen patients, 65 00:03:25,244 --> 00:03:28,093 we started with a standard, white light photograph, 66 00:03:28,117 --> 00:03:32,482 acquired either from a DSLR camera or a mobile phone, for the patient. 67 00:03:32,506 --> 00:03:34,974 Then remember those billions of information packets? 68 00:03:34,998 --> 00:03:38,498 We overlaid those from the medical image onto this image, 69 00:03:38,522 --> 00:03:41,474 creating something what we call a composite image. 70 00:03:41,498 --> 00:03:44,776 Much to our surprise, we only required 50 -- 71 00:03:44,800 --> 00:03:46,133 I repeat, only 50 -- 72 00:03:46,157 --> 00:03:50,022 of these composite images to train our algorithms to high efficiencies. 73 00:03:50,704 --> 00:03:52,029 To summarize our approach, 74 00:03:52,053 --> 00:03:55,220 instead of using 10,000 very expensive medical images, 75 00:03:55,244 --> 00:03:58,252 we can now train the AI algorithms in an unorthodox way, 76 00:03:58,276 --> 00:04:02,529 using only 50 of these high-resolution, but standard photographs, 77 00:04:02,553 --> 00:04:05,070 acquired from DSLR cameras and mobile phones 78 00:04:05,094 --> 00:04:06,617 and provide diagnosis. 79 00:04:06,641 --> 00:04:07,807 More importantly, 80 00:04:07,831 --> 00:04:11,029 our algorithms can accept, in the future and even right now, 81 00:04:11,053 --> 00:04:13,840 some very simple, white light photographs from the patient, 82 00:04:13,864 --> 00:04:16,593 instead of expensive medical imaging technologies. 83 00:04:17,165 --> 00:04:20,228 I believe that we are poised to enter an era 84 00:04:20,252 --> 00:04:22,167 where artificial intelligence 85 00:04:22,191 --> 00:04:24,720 is going to make an incredible impact on our future. 86 00:04:24,744 --> 00:04:27,202 And I think that thinking about traditional AI, 87 00:04:27,226 --> 00:04:29,998 which is data-rich but application-poor, 88 00:04:30,022 --> 00:04:31,569 we should also continue thinking 89 00:04:31,593 --> 00:04:34,601 about unorthodox artificial intelligence architectures, 90 00:04:34,625 --> 00:04:36,569 which can accept small amounts of data 91 00:04:36,593 --> 00:04:39,539 and solve some of the most important problems facing us today, 92 00:04:39,563 --> 00:04:40,801 especially in healthcare. 93 00:04:40,825 --> 00:04:42,000 Thank you very much. 94 00:04:42,024 --> 00:04:45,833 (Applause)