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[Mnamo Januari ya mwaka 2020,

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Christian Happi na Pardis Sabeti waliwasilisha wazo lenye uthubutu]

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[Sentinel: Mfumo wa ilani ya mapema katika kutambua na kufuatilia mlipuko wa gonjwa lijalo]

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[Hivi ni namna utavyofanya kazi ...]

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Christian Happi: Kiashiria ni mfumo wa ilani ya mapema iliyo amilifu katika kukinzana na magonjwa yanayoenea sana.

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Inajengwa na misingi mikuu mitatu.

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Pardis Sabeti: Msingi wa kwanza ni Utambuzi.

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Mimi na Christian tumekuwa tukitafiti pamoja magonjwa ya kuambukizwa

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duniani kote kwa miongo miwili.

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Tumekuwa tukitumia mfululizo wa jenomu.

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Tukizisoma taarifa timilifu za vinasaba vya vijidudu,

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inatusaidia kutambua virusi, hata vile ambavyo hatujawahi kuviona kabla,

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kuvifuatilia pale vinaposambaa

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na kuangazia mabadiliko yake mapya.

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Na sasa tukiwa na teknolojia yenye uwezo mkubwa wa kuziboresha chembe za urithi(jeni) iitwayo CRISPR,

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tunaweza kutumia taarifa hizi za kinasaba

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kutengeneza vipimo vya utambuzi vilivyo sahihi kwa vijidudu aina zote.

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CH: Moja ya nyenzo hizi zinafahamika kama SHERLOCK.

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Inaweza kutumika kutambua virusi vinavyotambulika katika vijikaratasi.

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Ni nafuu mno,

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na wafanyakazi wa afya walio mstari wa mbele wanaweza tumia SHERLOCK

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Kutambua virusi vinavyojulikana au vile ambavyo ni tishio

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ndani ya saa moja.

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PS: Nyenzo nyingine ni CARMEN.

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Inahitaji maabara, lakini inaweza kupima mamia ya virusi kwa wakati mmoja.

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Hivyo wafanyakazi wa maabara wanaweza pima sampuli za wagonjwa

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kutambua aina nyingi za virusi

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ndani ya siku moja.

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Msingi wetu wa pili ni Ungana.

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Kumuunganisha kila mmoja na kushirikishana taarifa

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kote katika jamii ya afya ya umma.

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Katika magonjwa mengi ya mlipuko,

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wafanyakazi wa hospitali hushirikishana taarifa kupitia nyaraka za karatasi.

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Hii hufanya ufatiliaji wa taarifa katika nafasi na nyakati

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na upatikanaji wa huduma

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kuwa mgumu sana.

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Hivyo tunatengeneza mfumo wa kimtandao na programu za simu

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ambazo zinawaunganisha wafanyakazi wa afya,

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waliopo zahanati, timu za afya umma -- kila mmoja --

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na kuwawezesha kuingiza taarifa,

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kufanya tathmini, kushirikishana vidokezo

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na kutengeneza mpango wa kuweza kuchukua hatua

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katika wakati sahihi.

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CH: Msingi wetu wa tatu ni Uwezeshaji.

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Mfumo wa uangalizi wa magonjwa ya mlipuko unaweza fanikiwa

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kama tutawawezesha wafanyakazi wa afya walio mstari wa mbele

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kuhudumia jamii.

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Inahitaji mafunzo mengi sana.

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Mimi na Pardis tunalitambua hilo.

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Tumetumia miaka kumi

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tukiwafunza mamia ya wanasayansi wadogo na wafanyakazi wa zanahati barani Afrika.

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Katika miaka mitano ijayo, tutaweza kutoa mafunzo kwa wahudumu wa afya wengine takribani 1,000

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katika kutumia mfumo wa Kiashiria

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na kuwawezesha pia kufundisha wafanyakazi wenzao.

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Namna hii, tutaweza kuboresha mfumo halisi wa afya

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na kuweza tumia uangalizi wa kina katika masuala ya kitabibu.

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[Tangu kuwakilisha mpango wao wa Uthubutu katika TED, ulimwengu umebadilika ...]

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Briar Goldberg: Tupo hapa, tunarekodi hili tukio.

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Ni tarehe 7 mwezi Aprili, 2020,

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na kwa uhakika, tupo katika tabu ya hili gonjwa ambalo ni janga la ulimwengu

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linalosababishwa na virusi vipya vya corona.

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Nyinyi wawili mmekuwa mkifanya kazi pamoja siku zote,

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na mlikuwa pamoja kwa juhudi

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katika janga la Ebola mwaka 2014.

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Mnalitazamaje hili jambo?

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CH: Miaka sita baada ya mlipuko wa Ebola,

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tumekumbana na janga lingine,

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na tupo katika wakati, ambao kwamba, hatujajifunza mengi kuhusu janga lililopita.

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Na hivyo, kiukweli, kwangu mimi, inanivunja moyo.

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PS: Ninadhani janga hili limetuonyesha ni namna gani hatukujiandaa

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duniani kote.

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Christian na washirika wetu pamoja tulikuwa na vikagua magonjwa katika hospitali zetu

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nchini Nigeria, Sierra Leone na Senegal mapema mwezi Februari.

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Majimbo mengi nchini Marekani hayakuwa navyo mpaka baadaye.

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Inatueleza kwamba wote tupo pamoja katika hili,

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na wote tupo nyuma .

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BG: Hivyo, huu mfumo wa Kiashiria ni mzuri,

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lakini nafahamu swali ambalo lipo akilini mwa kila mtu:

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Namna gani huu mfumo unasaidia sasa hivi?

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PS: Unajua, tumeelezea Kiashiria kama mfumo wa kuondokana na magonjwa yanayoenea sana,

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na hapa tupo katika moja ya magonjwa hayo.

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Lakini kilicho kikubwa ni kwamba, nyenzo zilezile unazohitaji

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kuondokana na gonjwa linaloenea

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ni zilezile unazohitaji kuondokana nalo.

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Na hivyo teknolojia ambazo tumeziainisha --

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Vipimo vyote vya awali vya uchaguzi,

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utambuzi na ufatiliaji wa virusi vinavyobadilika,

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na utumiaji wa programu za simu --

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ni muhimu mno.

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CH: Kwetu sisi, ni vita.

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Kimsingi tumejidhatiti katika ratiba ya masaa 24

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ili kuweza kutoa majibu,

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na inatuhitaji sisi kufanya kazi bila kupoteza muda.

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Hivyo ni nyakati yenye changamoto sana.

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Tupo mbali na familia.

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Angalau nina wasaha wa kuiona familia yangu leo,

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na kisha nina uhakika kesho ninarudi tena kwenye kazi.

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Katika maabara yangu, tumetengeneza mfululizo wa kwanza wa jenomu ya COVID-19

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katika bara la Afrika,

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na hilo lilifanyika ndani ya masaaa 48.

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Haya ni mapinduzi yanayotokea Afrika

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na kisha kufanya taarifa hizi kupatikana katika jamii ya masuala ya afya ulimwenguni

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ili kuona virusi vya Afrika vinaonekana katika namna gani.

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Ninaamini kwa kutumia teknolojia na maarifa

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na kisha kushirikisha taarifa,

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tunaweza fanya vizuri na kuweza kulishinda gonjwa.

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PS: Wazo zima la Sentinel

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ni katika kusimama wote kwa pamoja kulindana.

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Wote tunatazama.

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Kila mmoja wetu ni mlinzi.

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Kila mmoja wetu, anaweza tambua kipi kinachofanya sisi kuumwa,

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na kuweza kushirikisha jamii nzima taarifa hizo.

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Na nadhani hichi ndicho kitu ninachohitaji kiukweli,

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ni kwa wote kusimama kulindana

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na kutazamiana pamoja.

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[Dr. Pardis Sabeti na Dr. Christian Happi]

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[Wanasayansi wenye ustadi.

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Washirika wenye moyo.

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Mashujaa wa ulimwengu.]