0:00:14.763,0:00:17.130 Does the brain have a sex? 0:00:17.130,0:00:22.521 This is obviously a fundamental[br]question that everyone asks. 0:00:22.521,0:00:24.777 So, according to initial popular belief: 0:00:24.777,0:00:27.763 Women have a brain smaller than men, 0:00:27.763,0:00:30.789 therefore, they would be [br]less intelligent than men. 0:00:30.789,0:00:33.516 This idea stemmed from the 19th century, 0:00:33.516,0:00:36.523 during the heyday of craniometry 0:00:36.523,0:00:41.532 when doctors were interested to find [br]links between the size of the skull, 0:00:41.532,0:00:43.723 the weight of the brain and intelligence. 0:00:43.723,0:00:46.155 It's important to note [br]that for most of them 0:00:46.155,0:00:50.749 it was absolutely obvious and natural[br]that men had a bigger brain than women, 0:00:50.749,0:00:52.748 whites bigger than blacks 0:00:52.748,0:00:54.739 and managers bigger than workers. 0:00:55.259,0:00:57.220 A big supporter of these theories, 0:00:57.220,0:00:59.761 is the French doctor Paul Broca 0:00:59.761,0:01:02.503 who measured a difference of 150 grams 0:01:02.503,0:01:05.483 between average weights[br]of men's and women's brains, 0:01:05.483,0:01:08.533 men's weight was 1.350 kg 0:01:08.533,0:01:10.232 and women's 1.200 kg. 0:01:10.232,0:01:14.471 In 1861, Broca stated: 0:01:14.471,0:01:18.752 "We wondered if the smallness[br]of a woman's brain did not solely depend 0:01:18.752,0:01:21.972 on the smallness of her body, [br]nevertheless, one should not forget 0:01:21.972,0:01:25.259 that women on average [br]are a little less intelligent than men." 0:01:25.769,0:01:28.761 So, anyway, 0:01:28.761,0:01:32.493 this question of link between [br]the size of the brain and intelligence 0:01:32.493,0:01:33.775 is not asked anymore, 0:01:33.775,0:01:37.047 because the reality is, there is [br]no relation between the two, 0:01:37.047,0:01:40.201 and we know it thanks[br]to a certain number of male celebrities, 0:01:40.201,0:01:42.776 not women, who have given [br]their brains to science. 0:01:42.776,0:01:45.765 A prominent person[br]like Anatole France, for example, 0:01:45.765,0:01:48.228 had a brain that weighed one kilogram, 0:01:48.228,0:01:50.751 Tourgueniev had a brain that weighed 2 kg, 0:01:50.751,0:01:54.096 and as for Einstein,[br]he had a small brain weighing 1.250 kg. 0:01:54.096,0:01:57.179 Meaning, of the same size as women's. 0:01:57.179,0:02:01.255 Another popular belief: women are skilled[br]at doing more than one thing at a time 0:02:01.255,0:02:04.428 because the communications[br]between their brain's hemispheres 0:02:04.428,0:02:06.290 are more developed as oppose to men's. 0:02:06.290,0:02:10.526 We know very well, they're multi-tasking.[br]This idea comes from a study 0:02:10.526,0:02:13.072 published in 1982, 0:02:13.072,0:02:15.548 on 20 brains conserved in formalin 0:02:15.548,0:02:18.265 that showed that the corpus callosum, 0:02:18.265,0:02:20.234 that's the part surrounded by red, 0:02:20.234,0:02:23.946 the bundle of fibers that connects [br]both cerebral hemispheres, 0:02:23.946,0:02:27.011 that corpus callosum was thicker[br]for women than it was for men, 0:02:27.011,0:02:29.193 where perhaps better communication stems. 0:02:29.193,0:02:34.004 Now, since 1982, many things have gone by, 0:02:34.004,0:02:35.770 new technology developed, 0:02:35.770,0:02:40.286 in particular the new techniques[br]of cerebral imagery such as MRI 0:02:40.286,0:02:43.233 which made it possible[br]from then on to live the dream, 0:02:43.233,0:02:47.528 meaning to study a live brain[br]no more studying a brain in formalin. 0:02:47.528,0:02:49.770 And if we gather the collection of studies 0:02:49.770,0:02:53.236 made on this corpus callosum [br]since MRI was invented, 0:02:53.236,0:02:56.103 we realize that there is no difference[br]between men and women 0:02:56.103,0:02:58.016 in the thickness of the corpus callosum. 0:02:58.016,0:02:59.519 Another popular belief: 0:02:59.519,0:03:02.253 "Women are more capable [br]at learning languages 0:03:02.253,0:03:05.061 because they use both [br]of their hemispheres to speak." 0:03:05.061,0:03:06.884 Let's see where this also comes from: 0:03:06.884,0:03:10.752 this comes from a study[br]that was published in 1994, 0:03:10.752,0:03:14.530 a study using MRI during a language test, 0:03:14.530,0:03:17.510 and it showed that men, taking this test, 0:03:17.510,0:03:20.708 activated one hemisphere [br]whereas women used both. 0:03:20.708,0:03:24.516 So, this study that was conducted [br]on 19 men and women, 0:03:24.516,0:03:28.794 intrigued numerous researchers who[br]looked into reproducing these results. 0:03:29.235,0:03:32.516 And if we were to gather now[br]the collection of studies 0:03:32.516,0:03:37.778 that were published between 1995[br]and 2009, including this one, 0:03:37.778,0:03:40.714 in total, 700 men and women were tested, 0:03:40.714,0:03:42.774 we find that statically speaking, 0:03:42.774,0:03:45.504 there is no difference [br]between men and women 0:03:45.504,0:03:48.761 in the distribution of language areas. 0:03:48.761,0:03:52.508 And in fact, once a great number[br]of subjects were analyzed, 0:03:52.508,0:03:56.256 the difference between the sexes, [br]finally, disappeared. 0:03:56.256,0:03:58.237 We will see why. 0:03:58.237,0:04:01.259 Take this example, a study using MRI, 0:04:01.259,0:04:04.441 where we asked the subjects[br]to do a mental calculation 0:04:04.441,0:04:07.022 that they were all successful at doing. 0:04:07.022,0:04:10.073 We could then see[br]that in the women's group, 0:04:10.073,0:04:12.824 there was actually a great variability 0:04:12.824,0:04:15.516 in the distribution of areas in the brain 0:04:15.516,0:04:17.710 that were activated [br]during this calculation. 0:04:17.710,0:04:21.504 This variability was equally [br]found in the men's group. 0:04:22.034,0:04:26.082 Finally, to come to an even score[br]for mental calculation, 0:04:26.082,0:04:30.281 each individual has their own way [br]of activating their brain, 0:04:30.281,0:04:34.112 corresponding to many different strategies 0:04:34.112,0:04:36.764 to do mental calculations. 0:04:36.764,0:04:40.532 And, consequently, [br]the variability that we can observe 0:04:40.532,0:04:43.260 between the individuals of the same sex, 0:04:43.260,0:04:46.954 equals or exceeds[br]the variability between the sexes. 0:04:48.284,0:04:49.646 Another popular belief: 0:04:49.646,0:04:52.565 the differences of mental [br]aptitudes between the sexes 0:04:52.565,0:04:54.941 originates from a biological origin. 0:04:54.961,0:04:57.417 There are indeed a certain number of tests 0:04:57.417,0:05:00.030 where women are known to perform better. 0:05:00.030,0:05:03.767 For example tests[br]of visual perception of details, 0:05:03.767,0:05:05.284 such as this test here 0:05:05.284,0:05:08.044 where one must notice two identical houses 0:05:08.044,0:05:11.742 and the women are also better [br]at tests of verbal fluency, 0:05:11.742,0:05:14.257 where a maximum number [br]of words must be said 0:05:14.257,0:05:15.784 beginning with the same letter. 0:05:15.784,0:05:18.263 In short, all this is still [br]not very complicated. 0:05:18.263,0:05:22.813 When it comes to men, they are better,[br]or known to be better anyways, 0:05:22.813,0:05:27.281 at tests involving mental [br]rotation of objects in 3D. 0:05:27.842,0:05:30.979 They are equally better [br]at reaching a target. 0:05:30.979,0:05:35.502 So, based on the significance[br]of these differences in performance, 0:05:35.502,0:05:39.498 we can ask the question:[br]Are they inherent or are they acquired? 0:05:39.498,0:05:42.531 In fact, it must be noted [br]that the differences in question 0:05:42.531,0:05:46.220 are detectable only in adolescence, 0:05:46.220,0:05:49.253 and that they disappear with learning. 0:05:49.253,0:05:52.511 Therefore, we can assume[br]that education and culture 0:05:52.511,0:05:55.738 play an important role [br]in the emergence of these differences. 0:05:55.738,0:06:00.002 There is also another important factor,[br]which is the context 0:06:00.002,0:06:03.498 where these prominent tests are carried. 0:06:03.498,0:06:08.228 Let's take then this prominent test[br]of mental rotation in 3D, 0:06:08.228,0:06:11.892 where one must say [br]if the objects presented 0:06:11.892,0:06:15.018 are the same or if they are different. 0:06:15.018,0:06:17.762 If the test is given in a classroom 0:06:17.762,0:06:21.796 and the teacher says [br]this is a geometry test, 0:06:21.796,0:06:25.319 at that moment,[br]boys will be better than girls. 0:06:25.319,0:06:30.143 But if the teacher initially makes[br]an announcement that this is an art test, 0:06:30.143,0:06:33.473 at that moment, boys and girls[br]will have the same scores. 0:06:33.473,0:06:35.504 So, these results are interesting 0:06:35.504,0:06:40.579 which show how much self-esteem[br]and gender stereotypes 0:06:40.579,0:06:43.269 affect the results of the tests. 0:06:45.419,0:06:48.634 Another example also is the difference[br]in mathematical performances 0:06:48.634,0:06:52.398 between boys and girls, [br]in the United States. 0:06:52.398,0:06:56.536 A large-scale statistical survey[br]conducted on 10 million students 0:06:56.536,0:06:59.525 in 1990, showed, on average, 0:06:59.525,0:07:03.238 boys were a little better[br]than girls at math tests, 0:07:03.238,0:07:05.910 and some have interpreted [br]these results saying 0:07:05.910,0:07:09.457 that it was because girls did not have [br]a brain made for math. 0:07:09.457,0:07:12.943 But the same survey [br]that was commissioned in 2008, 0:07:12.943,0:07:16.551 shows equivalent scores[br]for boys and girls. 0:07:17.011,0:07:21.771 So, for 20 years we had a disappearance[br]of performance differences in math 0:07:21.771,0:07:23.283 between boys and girls, 0:07:23.283,0:07:25.994 which clearly shows [br]that it's the education 0:07:25.994,0:07:30.093 and not the biology that explains [br]these differences in scores. 0:07:30.093,0:07:31.893 Now, we will ask the question: 0:07:31.893,0:07:34.815 "How does education affect the brain?" 0:07:35.515,0:07:40.054 Our human brains are made up [br]of 100 billion neurons 0:07:40.054,0:07:42.006 that are connected to each other 0:07:42.006,0:07:47.045 thanks to connections[br]amounting to many billions. 0:07:47.045,0:07:51.541 Now 90% of these connections [br]develop after birth. 0:07:51.541,0:07:56.278 And it's precisely on how these [br]connections will come to be, 0:07:56.278,0:07:58.778 that these networks [br]of neurons will develop, 0:07:58.778,0:08:02.507 and where education and culture [br]will play an important part. 0:08:02.967,0:08:06.273 First example: [br]brains of professional pianists, 0:08:06.273,0:08:09.394 also applicable for violinists,[br]I assure you, 0:08:09.394,0:08:11.767 we can observe the MRI, for these people, 0:08:11.767,0:08:14.518 a thickness of the cerebral regions 0:08:14.518,0:08:19.019 which control the coordination[br]of fingers as well as the hearing. 0:08:19.019,0:08:21.210 In fact, this phenomenon of thickness 0:08:21.210,0:08:25.771 is due to the connections produced[br]between the extra neurons 0:08:25.771,0:08:27.799 and in addition it is proportional 0:08:27.799,0:08:32.080 to the time spent learning[br]the piano since childhood. 0:08:32.080,0:08:35.279 And we use the term cerebral plasticity 0:08:35.279,0:08:38.169 to describe the brain's ability 0:08:38.169,0:08:41.832 at shaping up eventually [br]to reflect experience. 0:08:41.832,0:08:44.861 Another example of cerebral[br]plasticity in adulthood. 0:08:44.861,0:08:48.162 We take a group[br]of twenty -year-old students 0:08:48.162,0:08:50.964 and we ask them to learn [br]to juggle three balls. 0:08:50.964,0:08:52.435 And in just three months, 0:08:52.435,0:08:55.256 we find this phenomenon[br]of the cortex thickening 0:08:55.256,0:08:59.208 in the regions that control[br]the motor coordination and vision. 0:08:59.208,0:09:02.273 So, what's really interesting[br]in this experiment is 0:09:02.273,0:09:04.784 that if the students[br]stop practice juggling, 0:09:04.784,0:09:08.961 eventually the regions[br]that thickened before will shrink. 0:09:08.961,0:09:11.830 And so, we strongly went ahead[br]with this experiment 0:09:11.830,0:09:15.050 with people who are [br]a little bit older, in their sixties, 0:09:15.050,0:09:18.590 and we find the same phenomenon[br]of thickness as the young ones. 0:09:18.590,0:09:20.030 It is still rather reassuring, 0:09:20.030,0:09:24.271 it shows that cerebral plasticity [br]persists with age. 0:09:25.481,0:09:28.257 Here we have an example[br]extremely extraordinary 0:09:28.257,0:09:30.049 of cerebral plasticity. 0:09:30.049,0:09:34.403 A man who is 44 years old, [br]married with two kids, 0:09:34.403,0:09:37.264 living a professional life[br]completely normal, 0:09:37.264,0:09:40.488 who suffered from slight [br]weakness in his leg. 0:09:40.488,0:09:43.770 We decided to do an MRI test[br]and surprise surprise, 0:09:43.770,0:09:48.505 we discovered that his skull[br]was essentially full of liquid 0:09:48.505,0:09:51.718 and his brain was reduced to a thin layer 0:09:51.718,0:09:54.333 flattened along [br]the inner lining of the skull. 0:09:54.333,0:09:56.233 We then asked questions. 0:09:56.233,0:10:00.239 And, it turns out, this person [br]suffered from hydrocephalus from birth, 0:10:00.239,0:10:02.995 so we placed a drain [br]at the base of the skull 0:10:02.995,0:10:07.721 to discharge the excess liquid,[br]but the drain was clogged 0:10:07.721,0:10:11.233 and finally the pressure[br]of the liquid repressed the brain 0:10:11.233,0:10:13.001 along the inner lining of the skull. 0:10:13.001,0:10:17.234 And all this happened without causing [br]any trouble in this patient's life 0:10:17.234,0:10:19.364 who never suspected anything. 0:10:19.934,0:10:23.749 So, now that you know[br]everything on cerebral plasticity, 0:10:23.749,0:10:26.895 in terms of the brain's structure[br]and function 0:10:26.895,0:10:29.959 which is modified in relation[br]to history for each person, 0:10:29.959,0:10:33.754 you can now then understand[br]why we all have very different brains, 0:10:33.754,0:10:35.218 regardless of sex. 0:10:35.218,0:10:37.703 However, what we do have in common 0:10:37.703,0:10:41.043 is this cerebral cortex [br]gifted with plasticity 0:10:41.043,0:10:44.002 which has greatly developed [br]in the course of evolution 0:10:44.002,0:10:48.449 and which had to crease in order [br]to fit inside the cranium. 0:10:48.979,0:10:52.290 You have here in front of you, [br]to the left, a real brain 0:10:52.290,0:10:56.069 and to the right, a model brain[br]with the technological means, 0:10:56.069,0:10:59.648 we can have fun by unfolding it virtually. 0:10:59.648,0:11:01.929 And I will give you this experience. 0:11:02.879,0:11:06.520 Here I am unveiling the brain, 0:11:06.520,0:11:08.252 well, the skull, actually. 0:11:08.712,0:11:11.241 I am opening the cranium 0:11:11.241,0:11:13.310 and I am unfolding the cerebral cortex 0:11:13.310,0:11:17.231 which measures 2 m² on 3 mm of thickness, 0:11:17.231,0:11:21.280 and it's because of this cerebral cortex[br]that all of us, men and women, 0:11:21.280,0:11:23.521 are able to reason, to think, 0:11:23.521,0:11:27.207 to dream and to imagine[br]the future of humanity. 0:11:27.207,0:11:28.457 Thank you. 0:11:28.457,0:11:31.057 (Applause)