A life-saving device that detects silent heart attacks
-
0:01 - 0:03When I was 13,
-
0:03 - 0:05I lost my grandfather
to a silent heart attack. -
0:06 - 0:10What happened to be more
shocking was that at 75, -
0:10 - 0:15grandpa was really normal,
healthy and energetic, -
0:15 - 0:17but he was diabetic.
-
0:18 - 0:20Learning all of this was so painful
-
0:20 - 0:24that I decided to go out on a war
against this deadly killer -
0:25 - 0:26and see what could be done.
-
0:27 - 0:30It was shocking to discover
the results of recent studies -
0:30 - 0:34that have shown an estimate
of nearly eight million people -
0:34 - 0:37who die from heart attacks every year.
-
0:38 - 0:40Heart attacks occur for many reasons,
-
0:40 - 0:45but most often, they occur
when arteries get clogged, -
0:45 - 0:47blood flow is cut off
-
0:47 - 0:50and oxygen-starved cells
in the heart muscles start to die. -
0:51 - 0:54You may know the common
symptoms of a heart attack: -
0:54 - 1:00chest pain, arm pain, shortness
of breath, fatigue, et cetera ... -
1:00 - 1:04but there is a type of heart attack
that is quite common, -
1:04 - 1:05just as deadly,
-
1:05 - 1:09but harder to detect
because the symptoms are silent. -
1:10 - 1:16People having silent heart attacks
just don't realize what's happening, -
1:16 - 1:19so they're not seeking medical attention,
-
1:19 - 1:24which means they're less likely
to receive the treatment that they need -
1:24 - 1:25at the critical moment.
-
1:27 - 1:30And even if they do
get to the hospital by chance, -
1:30 - 1:34either before or after
they are struck by a heart attack, -
1:34 - 1:39they might have to go through one or more
of these time-consuming, expensive tests -
1:39 - 1:40and treatments,
-
1:40 - 1:43which are currently considered
the gold standards -
1:43 - 1:45of heart-attack diagnosis.
-
1:45 - 1:47The greater concern, however,
-
1:47 - 1:51is that these silent heart attacks
account for nearly 45 percent -
1:51 - 1:53of all heart attacks.
-
1:54 - 1:58Patients with diabetes and similar
disorders suffer from nerve damage -
1:58 - 2:01that prevents them from feeling
the sort of pain -
2:01 - 2:04that usually signals to someone
-
2:04 - 2:08that he or she may be having
a heart attack. -
2:09 - 2:12Which means they suffer
the damage of a heart attack -
2:12 - 2:15without even knowing or feeling anything.
-
2:17 - 2:22These already at-risk patients
suffer from nerve damage, -
2:22 - 2:26and they do not get
immediate medical care. -
2:27 - 2:31They do not know anything before
an unlikely event is about to occur. -
2:32 - 2:35My grandfather
was an at-risk patient, too. -
2:36 - 2:39I probed this issue further --
-
2:39 - 2:42read as much as I could
to understand the heart, -
2:42 - 2:45met researchers
and worked across labs in India. -
2:46 - 2:51And finally, after three long years
of persistent research, -
2:51 - 2:55what I have to share with the world today
is a promising solution. -
2:56 - 2:59A noninvasive device that is inexpensive,
-
2:59 - 3:05portable, wearable by at-risk
patients at all times. -
3:06 - 3:09It greatly reduces
the need for a blood test -
3:09 - 3:15and works 24/7, collecting
and analyzing data at preset intervals. -
3:15 - 3:19And all this data is collected
for a single purpose: -
3:19 - 3:22detecting heart attacks as they occur.
-
3:23 - 3:28This is a very promising solution
that might help us in the future. -
3:29 - 3:32You may not know how intelligent
your heart really is. -
3:33 - 3:38It tries to communicate to your body
multiple times before failing, -
3:38 - 3:41by indicating symptoms like chest pain.
-
3:42 - 3:46These symptoms are triggered
when the heart loses out -
3:46 - 3:48on oxygen-rich blood flow.
-
3:49 - 3:51But remember I told you
about the nerve damage. -
3:52 - 3:56It silences these symptoms
before a silent heart attack, -
3:57 - 4:00which makes it even deadlier.
-
4:01 - 4:04And you may not even know
the common symptoms. -
4:06 - 4:10Meanwhile, the heart also sends out
certain biomarkers -- -
4:10 - 4:15cardiac biomarkers or proteins
that are SOS messages -- -
4:15 - 4:17in the form of SOS messages --
-
4:17 - 4:19into your bloodstream,
-
4:19 - 4:21indicating that the heart is at risk.
-
4:22 - 4:24As it gets riskier and riskier,
-
4:24 - 4:28the concentrations
of these cardiac biomarker proteins -
4:28 - 4:30keep increasing abysmally.
-
4:30 - 4:33My device solely relies on this data.
-
4:34 - 4:37The key is that these cardiac
biomarkers are found -
4:37 - 4:40in one of the earliest
stages of a heart attack, -
4:40 - 4:44when someone is almost sure to survive
-
4:44 - 4:47if he or she gets prompt care.
-
4:48 - 4:52And my device is solely based
on that basis. -
4:53 - 4:54And here's how my device works.
-
4:55 - 4:59A silicon patch is worn around your wrist
or placed near your chest. -
5:00 - 5:05Without having to prick your skin
for a biomarker blood test, -
5:05 - 5:12this patch can spot, isolate and track
a heart-attack specific biomarker -
5:12 - 5:14called H-FABP,
-
5:14 - 5:20and alerts you if and when it reaches
a critical level in your bloodstream -- -
5:20 - 5:25a process that's much simpler, easier
and cheaper than conventional methods -
5:26 - 5:28of heart-attack diagnosis.
-
5:29 - 5:33By checking on biomarker
concentration data, -
5:34 - 5:38a system like this,
with advanced research in the future, -
5:38 - 5:42could significantly reduce the need
for an at-risk patient to go to a doctor -
5:42 - 5:44for a biomarker blood test,
-
5:44 - 5:47because the device
could be worn at all times, -
5:47 - 5:50sensing biomarker elevations in real time.
-
5:51 - 5:57Thus, if the device senses the biomarker
levels going beyond the critical point, -
5:57 - 6:01the at-risk patient could be warned
of an impending cardiac arrest -
6:01 - 6:04and that he or she needs
immediate medical attention. -
6:05 - 6:08Although the device may not be able
to provide the patient -
6:08 - 6:11with the complete analysis
of the cardiac injury, -
6:11 - 6:13it might be of immense help
-
6:13 - 6:17in actually indicating
that the patient is in danger, -
6:17 - 6:19so that the patient can be alarmed
-
6:19 - 6:22and know that immediate care is crucial.
-
6:23 - 6:28Every at-risk patient will now receive
more time to survive -
6:28 - 6:30and reach out for medical help.
-
6:31 - 6:33Consequently, they don't have to go
-
6:33 - 6:36for expensive and invasive
medical treatments -
6:36 - 6:39that would otherwise be necessary
after a heart attack. -
6:41 - 6:45When I got my device tested
on at-risk patients under observation, -
6:45 - 6:48results from the clinical validation tests
-
6:48 - 6:52certified close to a 96 percent
accuracy and sensitivity. -
6:53 - 6:57I intend to make my device available
to people in two variants: -
6:57 - 7:01one which gives digital analysis
of the biomarker levels -
7:01 - 7:04and a simpler version
for the people in rural areas -
7:04 - 7:08which simply vibrates when the biomarker
levels go beyond the critical point. -
7:09 - 7:12When we look at our progress
in cardiac health care today, -
7:12 - 7:16it is more of sick care than preventative
self-care and technology. -
7:17 - 7:20We literally wait
for the heart attack to occur -
7:20 - 7:23and put our vast majority of resources
into post-care treatment. -
7:24 - 7:28But by then, irreversible damage
will already be done. -
7:29 - 7:32I firmly believe it's time
for us to rethink medicine. -
7:33 - 7:36We must establish proactive
health-care technologies. -
7:36 - 7:39A change must be brought out
not 10 years from now, -
7:39 - 7:40not five years from now,
-
7:40 - 7:42but today.
-
7:42 - 7:44And so, hopefully, one day,
-
7:44 - 7:46with the help of these devices,
-
7:46 - 7:50someone else won't lose
his or her grandfather just like I did. -
7:50 - 7:52Thank you so much.
-
7:52 - 7:53(Applause)
-
7:53 - 7:55Thank you.
-
7:55 - 7:57(Applause)
-
7:57 - 7:58Thank you.
- Title:
- A life-saving device that detects silent heart attacks
- Speaker:
- Akash Manoj
- Description:
-
You probably know the common symptoms of a heart attack: chest and arm pain, shortness of breath and fatigue. But there's another kind that's just as deadly and harder to detect because the symptoms are silent. In this quick talk, 17-year-old inventor Akash Manoj shares the device he's developed to stop this silent killer: a noninvasive, inexpensive, wearable patch that alerts patients during a critical moment that could mean the difference between life and death.
- Video Language:
- English
- Team:
- closed TED
- Project:
- TEDTalks
- Duration:
- 08:15
Brian Greene edited English subtitles for A life-saving device that detects silent heart attacks | ||
Brian Greene approved English subtitles for A life-saving device that detects silent heart attacks | ||
Brian Greene edited English subtitles for A life-saving device that detects silent heart attacks | ||
Krystian Aparta accepted English subtitles for A life-saving device that detects silent heart attacks | ||
Krystian Aparta edited English subtitles for A life-saving device that detects silent heart attacks | ||
Krystian Aparta edited English subtitles for A life-saving device that detects silent heart attacks | ||
Leslie Gauthier edited English subtitles for A life-saving device that detects silent heart attacks | ||
Leslie Gauthier edited English subtitles for A life-saving device that detects silent heart attacks |