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Trisomy and Monosomy

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    So Trisomy 21 or having three copies of
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    chromosome 21, is an example of aneuploidy, where
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    we gained a chromosome and this is referred
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    to clinically as Down's Syndrome. It's a disorder
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    which results in a delay of cognitive development,
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    physical growth as well a particular set of
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    facial features. Now monosomy X or XO, is
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    an example of aneuploidy from having lost a chromosome.
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    We only have one X chromosome and no Y chromosome or no other X chromosome. And
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    this is referred to as Turner's Syndrome, a
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    disorder with physical and hormonal abnormalities that result
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    in infertility. In general, aneuploidy has largely negative
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    effects. In fact, I haven't been able to
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    come up with one example where aneuploidy has
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    an overall net positive effect. Now for you advanced
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    learners out there, aneuploidy and polyploidy aren't
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    the same thing and there are net positive
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    effects to polyploidy. But if you can come
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    up with a good positive example, a net
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    positive example for aneuploidy, I would love it
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    if you go to the forums and post
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    it. I think we'd all like to see what a good example of that would be.
タイトル:
Trisomy and Monosomy
Video Language:
English
Team:
Udacity
プロジェクト:
BIO110 - Tales from the Genome
Duration:
01:12

English subtitles

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