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Octotales • Fred Hutch

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    I think the people
    who are going to cure cancer
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    are going to be the people
    who have competitional skills.
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    If people have programming skills,
    they can jump on and be a part of this.
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    And that's what we want,
    we want to get everyone involved.
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    We really think that the solution
    to unlocking cancer
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    is really going to be from all of us.
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    ♪ (music) ♪
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    (Eric Holland) The Fred Hutchinson
    Cancer Research Center
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    is a research center in Seattle
    that specializes in understanding cancer,
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    and coming up with new cures,
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    and that we can use for patients
    with diseases that are incurable.
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    (Lisa McFerrin) Our goal is to both
    research the cancer biology,
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    but also treat patients,
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    so a part of consortium
    that includes hospitals,
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    but also includes
    a large number of researchers.
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    (Eric) Historically, when people
    were trying to decide
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    what a cancer type was,
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    they would look under a microscope,
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    and because of the way things look,
    they would give it a name.
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    But recently, we've had the ability
    to sequence huge amounts of DNA,
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    and so, all of the sudden
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    there's a whole lot more
    sort of digital data
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    that completely describes a tumor
    in a much better way
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    that simply the way of microscope,
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    but this is both a good thing
    and a bad thing,
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    it poses a problem
    in that the amount of data
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    for any given person is enormous.
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    And all that information
    has to be compiled together
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    in some giant database,
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    and then manipulated and visualized,
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    and so we were able
    to get a team together
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    to attack this problem,
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    and we've built some of these tools,
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    that we're pretty happy with.
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    (Desert Horse-Grant) Oncoscape
    is an open source web application
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    where we take
    a cancer patient's information
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    and we easily visualize it
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    for doctors and scientists
    to understand
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    what's going on
    in the patient's disease.
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    The fields right now,
    there's cancer biologists,
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    so the people who are studying cancer,
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    and then there's the computational people,
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    and so we wanted a tool
    that really could speak to both groups,
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    and then at that same time
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    just how can we make the more together.
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    (Jenny Zhang) My work includes dry lab,
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    computational side plus the wet lab,
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    which means processing human tissues,
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    so I work on both sides.
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    So the tissue is freezed,
    I'll just put it on the dry ice,
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    and then switch to my [thermic up.]
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    A lot of time is we only look at data
    as a computer scientist,
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    but you don't know
    how the data were generated.
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    And I have this opportunity
    to look at the tissue,
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    and when the data doesn't make sense,
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    then you go back to the specimen.
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    Every aspect matters
    to generate good quality data.
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    There is a lot of advantages
    to be able to work on both sides.
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    (Eric) Well, I've been
    in this field for 20 years.
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    I've learned more about the disease
    that I'm particularly interested in,
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    which is brain cancer,
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    with simply this visualization
    to all I've learned
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    over many of the previous years,
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    because I'm not necessarily looking
    at only what [...] the street light,
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    you know, is iluminating.
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    If you look at all of the DNA,
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    you actually, it's like turning
    the lights on the entire room,
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    you see everything,
    and you see it all at once,
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    and you can see the things
    that you know exist,
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    but then there's always other stuff
    that you didn't even know to look for
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    but it's sitting right in front of you.
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    (Desert) So, we wanted Oncoscape
    to be open source,
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    because our goal,
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    and our goal from the beginning
    has really been about collaboration.
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    This year we got this idea
    because someone contacted us,
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    whose father had lung cancer,
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    but he really didn't have a way to help
    except for programming,
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    and it really gave us this idea
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    that coders out there
    could really help us.
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    And so, we thought this would be
    a great thing to put on GitHub,
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    and we felt like we could still
    give credit to people
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    and use their name
    and really celebrate them
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    for helping us in this fight
    against cancer.
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    (Lisa) You don't have to be an expert
    in biology or competitional biology.
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    We want to allow people
    to be an expert in their own field,
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    and so we've created
    all these "help wanted" tasks
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    on things that we're not experts at,
    that you might be an expert at,
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    and we want the "our GitHub repository"
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    to be a place where people can come to
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    and contribute their own knowledge,
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    their own software
    and their own efforts.
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    (Jenny) I know just by far
    how much I've been learning
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    from the GitHub community.
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    I've been checking
    a lot of the repositories
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    just looking at how they code.
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    We cannot work as competitors,
    any more in the cancer research,
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    because people die,
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    so we really need to work together
    with different cancer centers,
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    with different fields,
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    with people all from different expertise.
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    (Eric) It's a very saving time
    if these tools can be really brought
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    to the level that just any old person
    can do this, and you know,
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    it really opens up science
    in cancer research to everybody,
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    which is actually really exciting.
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    (Desert) I don't know, I mean,
    cancer will be solved on a computer.
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    We want people to join us
    in making a tool
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    that really all of us can benefit from.
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    ♪ (music) ♪
Cím:
Octotales • Fred Hutch
Leírás:

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Video Language:
English
Team:
GitHub
Projekt:
OctoTales
Duration:
06:03

English subtitles

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