English subtitles

← Steering and Reprogramming Life

Get Embed Code
2 Languages

Showing Revision 1 created 01/14/2019 by Paulo Henrique Ferreira.

  1. Not Synced
    Understanding the causal origins and
    mechanistic principles from the behavior
  2. Not Synced
    of an evolving system is one of the major
    challenges of our time.
  3. Not Synced
    For example, how a protein may fold to
    become a functional piece in your body
  4. Not Synced
    or how a drug may help against
    some disease.
  5. Not Synced
    A causal system can be described by an
    algorithmic model evolving over time.
  6. Not Synced
    The length of the shortest computer model
    is called
  7. Not Synced
    the algorithmic information content of
    the system.
  8. Not Synced
    That is how much computer code is needed
    to reproduce the object itself.
  9. Not Synced
    The shorter the description, the more
    likely the system is causally generated.
  10. Not Synced
    The longer its description, the less
    likely it is to be causally generated.
  11. Not Synced
    A dynamic system can usually be
  12. Not Synced
    as a network of interacting elements
  13. Not Synced
    such as interacting cells or interacting
    genes turning on and off other genes.
  14. Not Synced
    What we want is to figure out the first
    principles driving a system
  15. Not Synced
    such as a genetic network representing a
  16. Not Synced
    or the causes to the cell to behave in one
    way or another.
  17. Not Synced
    Power approach consistis in finding a set
    of algorithmic models that can explain
  18. Not Synced
    the structure of the system.
  19. Not Synced
    When the system is just a random process
    and therefore not causally generated
  20. Not Synced
    it can only be represented by a long
    descriptive model.
  21. Not Synced
    However, systems rich in causal content
    can be represented by a short model
  22. Not Synced
    because they have a generating mechanism
    that evolves
  23. Not Synced
    into any observable state of the system.
  24. Not Synced
    To determine the causal content of
    an evolving system
  25. Not Synced
    we peform perturbations.
  26. Not Synced
    In a network, for example, a perturbation
    can be deleting a node or deleting a link.
  27. Not Synced