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Showing Revision 1 created 09/27/2013 by Cogi-Admin.

  1. So we've finally gone through the first step
  2. of the central dogma, transcription, and we have
  3. our MRNA. So the second step of the
  4. central dogma is to turn that MRNA into protein
  5. using a process called translation. Translation relies heavily
  6. on the molecular machinery. On a component known
  7. as a ribosome. Ribosomes are the main driver
  8. of translation. Ribosomes are actually able to read an
  9. MRNA sequence by taking it in at one end and reading the MRNA sequence
  10. all the way through to the other end. And as it does this, it takes those 20
  11. amino acids And reads the code determining which
  12. amino acid belongs in a particular position. Now
  13. one of the most exciting puzzles of the 20th century, was to figure out how this
  14. code worked? I mean how is that this genetic code
  15. that these 4 letters and in what combination is that the
  16. [UNKNOWN]
  17. can read this. And add the right amino
  18. acid. Was it one base, one letter, per amino
  19. acid? If true, that would only give us
  20. four possible combinations: an A, a G, a C,
  21. or a U, and we know that we have at least 20 amino acids to get to.
  22. If it's two bases per amino acid Then
  23. that would only be sixteen possible combinations. Things like
  24. AG, AC, AU, GC, GA, GU, and so forth and so on. Only sixteen combinations
  25. but still 20 amino acids. So just extending
  26. that logic a little further, what's the minimum
  27. number of bases needed To have enough combinations
  28. to code for at least 20 amino acids.
  29. Go ahead and put the number that you think is best in this text box here.