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How the pandemic will shape the near future

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    Chris Anderson. Welcome, Bill Gates.
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    Bill Gates: Thank you.
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    CA: All right. It's great
    to have you here, Bill.
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    You know, we had a TED conversation
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    about three months ago
    about this pandemic,
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    and back then I think fewer than --
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    I think that was the end of March --
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    back then, fewer than
    a thousand people in the US had died,
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    and fewer than 20,000 worldwide.
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    I mean, the numbers now are,
    like, 128,000 dead in the US
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    and more than half a million worldwide.
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    in three months.
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    In three months.
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    What is your diagnosis of what is possible
    for the rest of this year?
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    You look at a lot of models.
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    What do you think best
    and worst case scenarios might be?
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    BG: Well, the range of scenarios, sadly,
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    is quite large, including that,
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    as we get into the fall,
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    we could have death rates
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    that rival the worst of what we had
    in the April time period.
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    If you get a lot of young people infected,
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    eventually they will infect
    old people again,
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    and so you'll get into the nursing homes,
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    the homeless shelters,
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    the places where we've had
    a lot of our deaths.
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    The innovation track,
    which probably we will touch on --
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    diagnostics, therapeutics, vaccines --
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    there's good progress there,
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    but nothing that would
    fundamentally alter the fact
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    that this fall in the United States
    could be quite bad,
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    and that's worse than
    I would have expected a month ago,
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    the degree to which we're back
    at high mobility,
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    not wearing masks,
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    and now the virus actually
    has gotten into a lot of cities
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    that it hadn't been in before
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    in a significant way,
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    so it's going to be a challenge.
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    There's no case where we get
    much below the current death rate,
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    which is about 500 deaths a day,
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    but there's a significant risk
    we'd go back up
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    to the even 2,000 a day
    that we had before,
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    because we don't have the distancing,
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    the behavior change,
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    to the degree that we had
    in April and May,
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    and we know this virus
    is somewhat seasonal,
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    so that the force of infection,
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    both through temperature, humidity,
    more time indoors,
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    will be worse as we get into the fall.
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    CA: So there are scenarios
    where in the US,
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    like, if you extrapolate
    those numbers forward,
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    we end up with, what,
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    more than a quarter of a million deaths,
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    perchance, even this year
    if we're not careful,
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    and worldwide I guess the death toll
    could by the end of the year
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    be well into the millions, with an s.
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    Is there evidence that the hotter
    temperatures of the summer
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    actually have been helping us?
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    BG: They're not absolutely sure,
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    but certainly the ?? model
    definitely wanted to use the season,
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    including temperature and humidity,
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    to try and explain why May
    wasn't worse than it was.
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    And so as we came out
    and the mobility numbers got higher,
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    the models expected more infections
    and deaths to come out of that,
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    and the model kept wanting to say,
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    "But I need to use this seasonality
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    to match why May wasn't worse,
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    why June wasn't worse than it was."
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    And we see in the Southern Hemisphere,
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    you know, Brazil,
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    which is the opposite season,
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    all of South America
    is having a huge epidemic.
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    South Africa is having
    a very fast-growing epidemic.
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    Fortunately, Australia and New Zealand,
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    the last countries
    in the Southern Hemisphere,
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    are at really tiny case counts,
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    and so although they have
    to keep knocking it down,
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    they're talking about, oh,
    we have 10 cases,
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    that's a big deal,
    let's go get rid of that.
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    So they're one of these amazing countries
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    that got the numbers so low
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    that test, quarantine and trace
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    is working to get them,
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    keep them at very near zero.
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    CA: Aided perhaps a bit
    by being easier to isolate
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    and by less density,
    less population density,
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    but nonetheless smart policies down there.
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    BG: Yeah. Everything is so exponential
    that a little bit of good work
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    goes a long ways.
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    It's not a linear game.
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    Contact tracing, if you have
    the number of cases we have in the US,
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    it's super-important to do,
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    but it won't get you back down to zero.
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    It'll help you be down,
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    but it's too overwhelming.
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    CA: OK, so in May and June in the US,
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    the numbers were actually slightly better
    than some of the models predicted,
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    and it's hypothesized that that might be
    partly because of the warmer weather.
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    Now we're seeing, really,
    would you describe it
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    as really quite alarming upticks
    in case rates in the US?
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    BG: That's right.
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    In, say, the New York area,
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    the cases continue to go down somewhat,
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    but in other parts of the country,
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    primarily the South right now,
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    you have increases
    that are offsetting that,
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    and you have testing
    positive rates in young people
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    that are actually higher
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    than what we saw even
    in some of the tougher areas,
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    and so clearly younger people
    have come out of mobility
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    more than older people
    have increased their mobility,
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    so the age structure
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    is right now very young, but
    because of multigenerational households,
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    people work in nursing care homes,
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    unfortunately that will work its way back,
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    both the time lag and the transmission
    back up into the elderly,
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    will start to push the death rate back up,
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    which it is down,
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    way down from 2,000
    to around 500 right now.
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    CA: And is that partly because
    there's a three-week lag
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    between case numbers and fatality numbers?
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    And also, perhaps, partly because
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    there have been
    some effective interventions
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    and we're actually seeing the possibility
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    that the overall fatality rate
    is actually falling a bit
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    now that we've gained
    some extra knowledge?
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    BG: Yeah, certainly
    your fatality rate is always lower
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    when you're not overloaded,
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    and so Italy when they were overloaded,
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    Spain, even New York at the start,
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    certainly China,
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    there you weren't even able
    to provide the basics,
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    the oxygen and things.
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    A study that our foundation
    funded in the UK
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    found the only thing
    other than remdesivir
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    that is a proven therapeutic,
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    which is the dexamethasone,
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    that for serious patients
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    is about a 20 percent death reduction,
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    and there's still quite
    a pipeline of those things.
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    You know, hydroxychloroquine
    never established positive data,
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    so that's pretty much done.
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    There's still a few trials ongoing,
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    but the list of things being tried,
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    including eventually
    monoclonal antibodies,
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    we will have some additional
    tools for the fall.
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    And so when you talk about death rates,
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    the good news is some
    innovation we already have
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    and we will have more
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    even in the fall.
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    We should start to have
    monoclonal antibodies,
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    which is the single therapeutic
    that I'm most excited about.
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    CA: I'll actually ask you to tell me
    a bit more about that in one sec,
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    but just putting the pieces
    together on death rates:
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    so in a well-functioning health system,
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    so take the US when places
    aren't overcrowded,
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    what do you think
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    the current fatality numbers
    are approximately going forward,
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    like as a percentage of total cases?
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    Are we below one percent, perhaps?
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    BG: If you found every case, yes,
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    you're well below one percent.
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    People argue, you know, 0.4, 0.5.
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    By the time you bring in
    the never symptomatics,
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    it probably is below 0.5,
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    and that's good news.
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    This disease could have been
    a five percent disease.
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    The transmission dynamics of this disease
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    are more difficult
    than even the experts predicted.
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    The amount of pre-symptomatic
    and never symptomatic spread,
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    and the fact that it's not coughing,
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    where you would kind of notice,
    hey, I'm coughing.
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    Most respiratory diseases make you cough.
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    This one, in its early stages,
    it's not coughing,
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    it's singing, laughing, talking,
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    actually still particularly
    for the super-spreaders,
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    people with very high viral loads,
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    causes that spread,
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    and that's pretty novel,
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    and so even experts have to say,
    wow, this caught us by surprise.
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    The amount of asymptomatic spread
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    and the fact that there's not
    a coughing element
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    is not a major piece like the flu or TB.
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    CA: Yeah, that is devilish cunning
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    by the virus.
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    I mean, how much is
    that non-symptomatic transmission
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    as a percentage of total transmission?
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    I've heard numbers it could be
    as much as half of all transmissions
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    are basically pre-symptomatic.
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    BG: Yeah, if you count pre-symptomatics,
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    then most of the studies show
    that's like at 40 percent,
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    and we also have never symptomatics.
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    The amount of virus you get
    in your upper respiratory area
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    is somewhat disconnected.
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    Some people will have a lot here
    and very little in their lungs,
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    and what you get in your lungs
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    causes the really bad symptoms,
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    and other organs,
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    but mostly the lungs,
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    and so that's when you seek treatment.
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    And so the worst case
    in terms of spreading
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    is somebody who's got a lot
    in the upper respiratory tract
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    but almost none in their lungs,
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    so they're not care-seeking.
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    CA: Right.
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    And so if you add in the never symptomatic
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    to the pre-symptomatic,
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    do you get above 50 percent
    of the transmission
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    is actually from non-symptomatic people?
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    BG: Yeah, transmission
    is harder to measure.
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    You know, we see certain
    hotspots and things,
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    but that's a huge question
    with the vaccine:
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    will it, besides avoiding
    you getting sick,
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    which is what the trial will test,
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    will it also stop you
    from being a transmitter?
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    CA: So that vaccine,
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    it's such an important question,
    let's come on to that,
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    but before we go there,
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    any other surprises
    in the last couple months
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    that we've learned about this virus
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    that really impact how
    we should respond to it?
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    BG: We're still not able to characterize
    who the super-spreaders are
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    in terms of what that profile is,
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    and we may never.
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    That may just be quite random.
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    If you could identify them,
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    they're responsible
    for the majority of transmission,
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    a few people who have
    very high viral loads.
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    But sadly, we haven't figured that out.
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    This mode of transmission,
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    if you're in a room and nobody talks,
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    there's way less transmission.
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    That's partly why,
    although planes can transmit,
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    it's less than you would expect
    just in terms of time proximity measures,
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    because unlike, say,
    a choir or a restaurant,
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    you're not exhaling in loud talking
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    quite as much as in
    other indoor environments.
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    CA: What do you think about the ethics
    of someone who would go on a plane
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    and refuse to wear a mask?
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    BG: If they own the plane,
    that would be fine.
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    If there's other people on the plane,
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    that would be endangering
    those other people.
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    CA: Early on in the pandemic,
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    the WHO did not advise
    that people wear masks.
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    They were worried about taking them away
    from frontline medical providers.
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    In retrospect, was that
    a terrible mistake that they made?
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    BG: Yes.
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    All the experts feel bad
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    that the value of masks,
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    which ties back somewhat
    to the asymptomatics,
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    if people were very symptomatic,
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    like an Ebola,
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    then you know it and you isolate,
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    and so you don't have
    a need for a mask-like thing.
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    The value of masks,
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    the fact that the medical masks
    was a different supply chain
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    than the normal masks,
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    the fact you could scale up
    the normal masks so well,
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    the fact that it would stop
    that pre-symptomatic,
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    never symptomatic transmission,
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    it's a mistake,
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    but it's not a conspiracy,
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    it's something that we now know more.
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    And even now, our error bars
    on the benefit of masks
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    are higher than we'd like to admit,
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    but it's a significant benefit.
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    CA: All right, I'm going to come in
    with some questions
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    from the community.
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    Let's pull them up there.
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    Jim Pitofsky: "Do you think reopening
    efforts in the US have been premature,
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    and if so how far should the US go
    to responsibly confront this pandemic?"
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    BG: Well, the question
    of how you make tradeoffs
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    between the benefits, say,
    of going to school
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    versus the risk of people getting sick
    because they go to school,
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    those are very tough questions
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    that I don't think any single person
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    can say, "I will tell you
    how to make all these tradeoffs."
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    The understanding of
    where you have transmission,
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    and the fact that young people
    do get infected
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    and are part of the multi-generational
    transmission chain,
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    we should get that out.
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    If you just look at the health aspect,
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    we have opened up too liberally.
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    Now, opening up in terms of mental health
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    and seeking normal health things
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    like vaccines and other care,
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    there are benefits.
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    I think some of our opening up
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    has created more risk than benefit.
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    Opening the bars up
    as quickly as they did,
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    is that critical for mental health?
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    Maybe not.
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    So I don't think we've been
    as tasteful about opening up
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    as I'm sure, as we study it,
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    that we'll realize some things
    we shouldn't have opened up as fast,
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    but then you have something like school,
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    where even sitting here today,
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    the exact plan, say,
    for inner city schools for the fall,
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    I wouldn't have a black-and-white view
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    on the relative tradeoffs involved there.
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    There are huge benefits
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    to letting those kids go to school,
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    and how do you weigh the risk?
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    If you're in a city
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    without many cases,
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    I would say probably the benefit is there.
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    Now that means that
    you could get surprised.
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    The cases could show up,
    and then you'd have to change that,
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    which is not easy.
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    But I think around the US
    there will be places
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    where that won't be a good tradeoff.
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    So almost any dimension and inequity,
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    this disease has made worse:
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    job type, internet connection,
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    ability of your school
    to do online learning.
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    White collar workers,
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    people are embarrassed to admit it,
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    some of them are more productive
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    and enjoying the flexibility
    that the at-home thing has created,
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    and that feels terrible
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    when you know lots of people
    are suffering in many ways,
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    including their kids not going to school.
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    CA: Indeed. Let's have the next question.
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    "For us in Rwanda,
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    early policy interventions
    have made the difference.
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    At this point, what policy interventions
    do you suggest for the US now?"
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    Bill, I dream of the day
    where you are appointed
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    the coronavirus czar
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    with authority to actually
    speak to the public.
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    What would you do?
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    BG: The innovation tools
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    are where I and the foundation
    probably has the most expertise.
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    Clearly some of the policies
    on opening up have been too generous,
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    but I think everybody
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    could engage in that.
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    We need leadership
  • 17:38 - 17:40
    in terms of admitting
  • 17:40 - 17:43
    that we've still got a huge problem here,
  • 17:43 - 17:47
    and not turning that
    into almost a political thing
  • 17:47 - 17:52
    of, oh, isn't it brilliant what we did.
  • 17:52 - 17:54
    No, it's not brilliant,
  • 17:54 - 17:56
    but there's many people,
  • 17:56 - 17:58
    including the experts,
  • 17:58 - 18:01
    where there's a lot
    they didn't understand,
  • 18:01 - 18:05
    and everybody wishes a week earlier
    whatever action they took,
  • 18:05 - 18:07
    they'd taken that a week earlier.
  • 18:07 - 18:10
    The innovation tools,
  • 18:10 - 18:13
    that's where the foundation's work
  • 18:13 - 18:18
    on antibodies, vaccines,
  • 18:18 - 18:21
    we have deep expertise,
  • 18:21 - 18:24
    and it's outside of the private sector,
  • 18:24 - 18:28
    and so we have kind of a neutral ability
    to work with all the governments
  • 18:28 - 18:31
    and the companies to pick.
  • 18:31 - 18:33
    Particularly when you're doing
    break-even products,
  • 18:33 - 18:35
    which one should get the resources.
  • 18:35 - 18:37
    There's no market signal for that.
  • 18:37 - 18:43
    Experts have to say, OK,
    this antibody deserves the manufacturing.
  • 18:43 - 18:45
    This vaccine deserves the manufacturing.
  • 18:45 - 18:50
    Because, we have very limited
    manufacturing for both of those things,
  • 18:51 - 18:54
    and it'll be cross-company,
  • 18:54 - 18:55
    which never happens in the normal case,
  • 18:55 - 18:56
    where one company invents it
  • 18:56 - 18:59
    and then you're using
    the manufacturing plants
  • 18:59 - 19:01
    of many companies
  • 19:01 - 19:04
    to get maximum scale of the best choice.
  • 19:04 - 19:07
    So I would be coordinating those things,
  • 19:07 - 19:12
    but we need a leader
    who keeps us up to date,
  • 19:12 - 19:14
    is realistic,
  • 19:14 - 19:17
    and shows us the right behavior,
  • 19:17 - 19:19
    as well as driving the innovation track.
  • 19:19 - 19:21
    CA: I mean, you have to yourself
    be a master diplomat
  • 19:21 - 19:24
    in how you talk about this stuff.
  • 19:24 - 19:27
    So I appreciate, almost,
    the discomfort here,
  • 19:27 - 19:29
    but you talk regularly with Anthony Fauci,
  • 19:29 - 19:35
    who is a wise voice on this
    by most people's opinion.
  • 19:35 - 19:37
    But to what extent is he just hamstrung?
  • 19:37 - 19:40
    He's not allowed to play the full role
  • 19:40 - 19:43
    that he could play in the circumstance.
  • 19:43 - 19:45
    BG: Dr. Fauci has emerged,
  • 19:45 - 19:49
    where he was allowed to have some airtime,
  • 19:49 - 19:53
    and even though he was stating
    things that are realistic,
  • 19:53 - 19:55
    his prestige has stuck.
  • 19:55 - 19:57
    He can speak out in that way.
  • 19:57 - 20:01
    Typically, the CDC would be
    the primary voice here.
  • 20:02 - 20:06
    It's not absolutely necessary,
  • 20:06 - 20:07
    but in previous health crises,
  • 20:07 - 20:10
    you let the experts inside the CDC
  • 20:10 - 20:12
    be that voice.
  • 20:12 - 20:14
    They're trained to do these things,
  • 20:14 - 20:17
    and so it is a bit unusual here
  • 20:17 - 20:20
    how much we've had to rely on Fauci
  • 20:20 - 20:22
    as opposed to the CDC.
  • 20:22 - 20:26
    It should be Fauci,
    who is a brilliant researcher,
  • 20:26 - 20:29
    so experienced, particularly in vaccines,
  • 20:29 - 20:33
    in some ways he has become,
    taking the broad advice
  • 20:33 - 20:36
    that is the epidemiology advice
  • 20:36 - 20:40
    and explaining it in the right way,
  • 20:40 - 20:41
    where he'll admit,
  • 20:41 - 20:44
    "OK, we may have a rebound here,
  • 20:44 - 20:48
    and this is why we need
    to behave that way."
  • 20:48 - 20:53
    But it's fantastic that his voice
    has been allowed to come through.
  • 20:54 - 20:56
    CA: Sometimes.
  • 20:56 - 20:58
    Let's have the next question.
  • 21:00 - 21:04
    Nina Gregory: "How are you
    and your foundation
  • 21:04 - 21:07
    addressing the ethical questions
    about which countries
  • 21:07 - 21:09
    get the vaccine first,
  • 21:09 - 21:11
    assuming you find one?"
  • 21:11 - 21:13
    And maybe, Bill, use this as a moment
  • 21:13 - 21:16
    to just talk about where
    the quest for the vaccine is
  • 21:16 - 21:20
    and what are just some of the key things
    we should all be thinking about
  • 21:20 - 21:22
    as we track the news on this.
  • 21:22 - 21:27
    BG: There's three vaccines that are,
  • 21:27 - 21:29
    if they work, are the earliest:
  • 21:29 - 21:34
    the Moderna, which unfortunately
    won't scale very easily,
  • 21:35 - 21:39
    so if that works, it'll be mostly
    a US-targeted thing;
  • 21:39 - 21:42
    then you have the AstraZeneca,
    which comes from Oxford;
  • 21:42 - 21:44
    and the Johnson & Johnson.
  • 21:44 - 21:46
    Those are the three early ones,
  • 21:46 - 21:48
    and we have animal data
  • 21:48 - 21:52
    that looks potentially good,
  • 21:52 - 21:54
    but not definitive,
  • 21:54 - 21:57
    particularly will it work in the elderly,
  • 21:57 - 22:00
    and we'll have human data
    over the next several months.
  • 22:00 - 22:06
    Those three will be gated by
    the safety and efficacy trial.
  • 22:06 - 22:08
    That is, we'll be able
    to manufacture those,
  • 22:08 - 22:11
    although not as much as we want.
  • 22:11 - 22:13
    We'll be able to manufacture those
    before the end of the year.
  • 22:13 - 22:15
    Whether the Phase 3 will succeed,
  • 22:15 - 22:18
    and whether it'll complete
    before the end of the year,
  • 22:18 - 22:22
    I wouldn't be that optimistic about.
  • 22:22 - 22:26
    Phase 3 is where you need
    to really look at all the safety profile
  • 22:26 - 22:28
    and efficacy,
  • 22:28 - 22:30
    but those will get started.
  • 22:30 - 22:32
    And then there's four or five vaccines
  • 22:32 - 22:34
    that use different approaches
  • 22:34 - 22:37
    that are maybe three
    or four months behind that:
  • 22:37 - 22:40
    Novavax, Sanofi, Merck.
  • 22:41 - 22:48
    And so we're funding factory capacity
    for a lot of these --
  • 22:48 - 22:54
    some complex negotiations
    are taking place right now on this --
  • 22:54 - 22:58
    to get factories that will be dedicated
    to the poorer countries,
  • 22:59 - 23:02
    what's called low- and middle-income.
  • 23:02 - 23:04
    And the very scalable constructs
  • 23:04 - 23:09
    that include AstraZeneca
    and Johnson & Johnson,
  • 23:09 - 23:11
    we'll focus on those,
  • 23:11 - 23:12
    the ones that are inexpensive
  • 23:12 - 23:16
    and you can build a single factory
    to make 600 million doses.
  • 23:16 - 23:20
    So a number of the vaccine constructs
  • 23:20 - 23:21
    are potential.
  • 23:21 - 23:26
    I don't see anything
    before the end of the year.
  • 23:26 - 23:27
    That's really the best case,
  • 23:27 - 23:31
    and it's down to a few constructs now,
  • 23:31 - 23:35
    which typically you have
    high failure rates.
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    CA: Bill, is the case
  • 23:38 - 23:41
    that you and your foundation
    weren't in the picture here
  • 23:41 - 23:44
    that market dynamics would likely
    lead to a situation
  • 23:44 - 23:48
    where as soon as a promising
    vaccine candidate emerged,
  • 23:48 - 23:50
    the richer countries
    would basically snap up,
  • 23:50 - 23:54
    gobble up all available initial supply --
  • 23:54 - 23:55
    it just takes a while
    to manufacture these --
  • 23:55 - 23:59
    and there would be nothing
    for the poorer countries,
  • 23:59 - 24:02
    but that what effectively you're doing,
  • 24:02 - 24:04
    by giving manufacturing guarantees
  • 24:04 - 24:07
    and capability to some
    of these candidates,
  • 24:07 - 24:13
    you're making it possible that
    at least some of the early vaccine units
  • 24:14 - 24:16
    will go to poorer countries?
  • 24:16 - 24:17
    Is that correct?
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    BG: Well, it's not just us, but yes,
  • 24:19 - 24:21
    we're in the central role there
  • 24:21 - 24:25
    along with a group we created called CEPI,
  • 24:25 - 24:28
    Coalition for Epidemic Preparedness,
  • 24:28 - 24:32
    and the European leaders agree with this.
  • 24:32 - 24:35
    Now we have the expertise
    to look at each of the constructs
  • 24:35 - 24:38
    and say, OK, where is there
    a factory in the world
  • 24:38 - 24:40
    that has capacity that can build that?
  • 24:40 - 24:43
    Which one should we put
    the early money into?
  • 24:43 - 24:45
    What should the milestones be
  • 24:45 - 24:48
    where we'll shift the money
    over to a different one?
  • 24:48 - 24:52
    Because the kind of private sector people
  • 24:52 - 24:54
    who really understand that stuff,
  • 24:54 - 24:56
    some of them work for us,
  • 24:56 - 25:00
    and we're a trusted party on these things,
  • 25:00 - 25:04
    we get to coordinate a lot,
    particularly that manufacturing piece.
  • 25:05 - 25:07
    Usually, you'd expect the US
  • 25:07 - 25:11
    to think of this as
    a global problem and be involved.
  • 25:11 - 25:18
    So far, no activity
    on that front has taken place.
  • 25:18 - 25:22
    I am talking to people in the Congress
    and the Administration
  • 25:22 - 25:25
    about when the next
    relief bill comes along
  • 25:25 - 25:28
    that maybe one percent of that
  • 25:28 - 25:30
    could go for the tools
  • 25:30 - 25:32
    to help the entire world.
  • 25:32 - 25:35
    And so it's possible,
  • 25:35 - 25:37
    but it's unfortunate,
  • 25:37 - 25:40
    and the vacuum here
  • 25:40 - 25:42
    the world is not that used to
  • 25:42 - 25:45
    and a lot of people are stepping in,
  • 25:45 - 25:46
    including our foundation,
  • 25:46 - 25:49
    to try and have a strategy,
  • 25:49 - 25:51
    including for the poorer countries
  • 25:51 - 25:57
    who will suffer a high percentage
    of the deaths and negative effects,
  • 25:57 - 26:00
    including their health systems
    being overwhelmed.
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    Most of the deaths will be
    in developing countries,
  • 26:03 - 26:07
    despite the huge deaths we've seen
    in Europe and the US.
  • 26:07 - 26:11
    CA: I mean, I wish I could be
    a fly on the wall and hearing
  • 26:11 - 26:12
    you and Melinda talk about this,
  • 26:12 - 26:17
    because of all of
    the ethical crimes, let's say,
  • 26:17 - 26:20
    executed by leaders
    who should know better,
  • 26:21 - 26:26
    I mean, it's one thing
    to not model mask-wearing,
  • 26:26 - 26:29
    but to not play a role
  • 26:29 - 26:33
    in helping the world when faced
    with a common enemy,
  • 26:33 - 26:36
    respond as one humanity
  • 26:36 - 26:43
    and instead catalyze a really unseemly
    scramble between nations
  • 26:43 - 26:46
    to fight for vaccines, for example.
  • 26:46 - 26:51
    That just seems that surely history
    is going to judge that harshly.
  • 26:51 - 26:54
    That is just sickening.
  • 26:54 - 26:57
    Isn't it? Am I missing something?
  • 26:57 - 27:03
    BG: Well, it's not quite
    as black and white as that.
  • 27:03 - 27:05
    The US has put more money out
  • 27:05 - 27:09
    to fund the basic research
    on these vaccines
  • 27:09 - 27:11
    than any country by far,
  • 27:11 - 27:14
    and that research is not restricted.
  • 27:14 - 27:18
    There's not, like, some royalty
    that says, "Hey, if you take our money,
  • 27:18 - 27:20
    you have to pay the US a royalty."
  • 27:20 - 27:23
    They do, to the degree they fund research,
  • 27:23 - 27:24
    it's for everybody.
  • 27:24 - 27:27
    To the degree they fund factories,
    it's just for the US.
  • 27:27 - 27:31
    The thing that makes this tough is that
    in every other global health problem,
  • 27:31 - 27:34
    the US totally leads smallpox eradication,
  • 27:34 - 27:39
    the US is totally the leader
    on polio eradication
  • 27:39 - 27:45
    with key partners -- CDC, WHO,
    Rotary, UNICEF, our foundation.
  • 27:45 - 27:48
    So the world, and on HIV,
  • 27:48 - 27:53
    what under President Bush's leadership,
    but it was very bipartisan,
  • 27:53 - 27:57
    this thing called PEPFAR was unbelievable.
  • 27:57 - 27:59
    That has saved tens of millions of lives.
  • 27:59 - 28:03
    And so it's that the world
    always expected the US
  • 28:03 - 28:05
    to at least be at the head of the table,
  • 28:05 - 28:10
    financially, strategy, OK, how do you
    get these factories for the world,
  • 28:10 - 28:15
    even if it's just to avoid the infection
    coming back to the US
  • 28:15 - 28:17
    or to have the global economy working,
  • 28:17 - 28:19
    which is good for US jobs
  • 28:19 - 28:22
    to have demand outside the US.
  • 28:22 - 28:26
    And so the world is kind of,
    there's all this uncertainty
  • 28:26 - 28:27
    about which thing will work,
  • 28:27 - 28:31
    and there's, OK, who is in charge here?
  • 28:31 - 28:34
    And so the worst thing,
  • 28:34 - 28:36
    the withdrawal from WHO,
  • 28:36 - 28:38
    that is a difficulty
  • 28:38 - 28:44
    that hopefully will
    get remedied at some point,
  • 28:44 -
    because we need that coordination
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    through WHO.
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    CA: Let's take another question.
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    Ali Kashani: "Are there any
    particularly successful models
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    of handling the pandemic
    that you have seen around the world?"
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    BG: Well, it's fascinating that,
    besides early action,
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    there are definitely things where
    you take people who have tested positive
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    and you monitor their ??,
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    which is a oxygen saturation
    level in their blood,
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    which is a very cheap detector,
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    and then you know to get them
    to the hospitals fairly early.
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    Weirdly, patients don't know
    things are about to get severe.
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    It's an interesting physiological reason
    but I won't get into.
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    And so Germany has
    a quite a low case fatality rate
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    that they've done through
    that type of monitoring.
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    And then, of course,
    once you get into facilities,
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    we've learned that the ventilator
    actually, although extremely well-meaning,
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    was actually overused
    and used in the wrong mode
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    in those early days.
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    So the health, the doctors
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    are way smarter about treatment today.
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    Most of that I would say is global.
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    Using this ??
    as an early indicator,
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    that'll probably catch on broadly,
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    but Germany was a pioneer there.
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    And now, of course, dexamethasone,
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    fortunately, it's cheap, it's oral,
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    we can ramp up manufacture.
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    That'll go global as well.
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    CA: Bill, I want to ask you
  • Not Synced
    something about
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    what it's been like for you personally
    through this whole process.
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    Because, weirdly, even though
    your passion and good intent on this topic
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    seems completely bloody obvious to anyone
    who has spent a moment with you,
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    there are these crazy
    conspiracy theories out there about you.
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    I just checked in
    with a company called Zignal
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    that monitors social media spaces.
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    They say that, to date,
    I think on Facebook alone,
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    more than four million posts
    have taken place
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    that associate you with some kind
    of conspiracy theory around the virus.
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    I read that there was a poll
    that more than 40 percent of Republicans
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    believe that the vaccine
    that you would roll out
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    would somehow plant a microchip
    in people to track their location.
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    I mean, I can't even believe
    that poll number.
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    And then some people
    are taking this seriously enough,
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    and some of them have even been
    recirculated on Fox News and so forth,
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    some people are taking this
    seriously enough
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    to make really quite horrible
    threats and so forth.
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    You seem to do a good job
    sort of shrugging this off,
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    but really, like, who else
    has ever been in this position?
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    How are you managing this?
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    What on earth world are we in
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    that this kind of misinformation
    can be out there?
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    What can we do to help correct it?
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    BG: I'm not sure,
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    and it's a new thing
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    that there's conspiracy theories.
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    I mean, Microsoft had
    its share of controversy,
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    but at least that related
    to the real world, you know?
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    Did Windows crash more than it should?
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    We definitely had anti-trust problems.
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    But at least I knew what that was.
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    When this emerged, I have to say,
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    my instinct was to joke about it.
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    People have said
    that's really inappropriate,
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    because this is a very serious thing.
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    It is going to make people
    less willing to take a vaccine.
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    And, of course, once we have that vaccine,
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    it'll be like masks,
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    where getting lots of people,
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    particularly when it's
    a transmission-blocking vaccine,
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    there's this huge community benefit
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    to widespread adoption of that vaccine.
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    So I am caught a little bit,
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    unsure of what to say or do,
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    because the conspiracy piece
    is a new thing for me,
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    and what do you say
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    that doesn't give credence to the thing?
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    The fact that a Fox News commentator,
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    Laura Ingraham, was saying
    this stuff about me microchipping people,
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    that survey isn't that surprising
    because that's what they heard
  • Not Synced
    on the TV.
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    It's wild.
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    And people are clearly seeking
    simpler explanations
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    than going and studying virology.
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    CA: I mean,
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    TED is nonpolitical,
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    but we believe in the truth.
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    I would say this.
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    Laura Ingraham, you owe Bill Gates
    an apology and a retraction.
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    You do.
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    And anyone who is watching this
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    who thinks for a minute
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    that this man is involved
    in some kind of conspiracy,
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    you want your head examined.
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    You are crazy.
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    Enough of us know Bill over many years
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    and have seen the passion
    and engagement in this to know
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    that you are crazy.
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    So get over it,
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    and let's look at the actual problem
    of solving this pandemic.
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    Honestly.
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    If anyone in the chat here
    has a suggestion,
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    a positive suggestion for how you can,
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    how do you get rid of conspiracies,
    because they feed on each other.
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    Now, oh, well I would say that,
    because I'm part of the conspiracy,
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    or whatever.
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    Like, how do we get back to a world
    where information can be trusted?
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    We have to do better on it.
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    Are there any other questions
    out there from the community?
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    Aria Bendix from New York City:
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    "What are your personal recommendations
    for those who want to reduce
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    their risk of infection
    amid an uptick in cases?"
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    BG: Well, it's great if you have a job
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    that you can stay at your house
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    and do it through digital meetings,
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    and even some of your social activities,
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    you know, I do video calls
    with lots of friends.
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    I have friends in Europe that
    who knows when I'll see them
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    but we schedule regular calls to talk.
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    If you stay fairly isolated,
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    you don't run much risk,
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    and it's when you're getting together
    with lots of other people,
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    either through work or socialization,
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    that drives that risk,
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    and particularly in these communities
    where you have increased cases,
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    even though it's not going to be mandated,
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    hopefully the mobility numbers
    will show people responding
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    and minimizing those kind of
    out of the house contacts.
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    CA: Bill, I wonder if I could just ask you
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    just a little bit about philanthropy.
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    Obviously your foundation
    has played a huge role in this,
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    but philanthropy more generally.
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    You know, you've started
    this giving pledge movement,
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    recruited all these billionaires
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    who have pledged to give away
    half their net worth
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    before or after their death.
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    But it's really hard to do.
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    It's really hard to give away
    that much money.
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    You yourself, I think,
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    since the giving pledge was started,
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    what, 10 years ago or something,
    I'm not sure when,
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    but your own net worth I think
    has doubled since that period
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    despite being the world's
    leading philanthropist.
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    Is it just fundamentally hard
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    to give away money effectively
    to make the world better?
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    Or should the world's donors,
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    and especially the world's
    really rich donors,
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    start to almost commit to a schedule,
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    like, here's a percentage
    of my net worth each year
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    that as I get older,
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    maybe that goes up.
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    If I'm to take this seriously,
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    I have to give away, somehow,
    I've got to find a way
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    of doing that effectively.
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    Is that an unfair and crazy question?
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    BG: Well, it'd be great to up the rate,
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    and our goal, both as the Gates Foundation
    or through the giving pledge,
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    is to help people find causes
    they connect to.
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    People give through passion.
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    Yes, numbers are important,
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    but there's so many causes out there.
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    The way you're going to pick
    is you see somebody who is sick,
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    you see somebody who is not
    getting social services.
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    You see something
    that helps reduce racism.
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    And you're very passionate,
    and so you give to that.
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    And, of course,
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    some philanthropic gifts won't work out.
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    We do need to up the ambition level
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    of philanthropists.
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    Now, collaborative philanthropy
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    that you're helping to facilitate
    through Audacious,
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    there's four or five other groups
    that are getting philanthropists together,
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    that is fantastic,
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    because then they learn from each other,
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    they get confidence from each other,
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    they feel like, hey, I put in x
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    and the four other people put money in,
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    so I'm getting more impact,
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    and hopefully it can be made for them
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    even when they find out,
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    OK, that particular gift
    didn't work out that well,
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    but let's keep going.
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    So philanthropy, yes,
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    I would like to see the rate go up,
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    and people who do get going,
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    it is fun,
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    it's fulfilling,
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    you pick which of the family members
    are partnered in doing it.
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    In my case, Melinda and I
    love doing this stuff together,
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    learning together.
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    Some families, it will even
    involve the kids in the activities.
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    Sometimes the kids are pushing.
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    When you have lots of money,
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    you still think of million dollars
    as a lot of money,
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    but if you have billions,
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    you should be giving hundreds of millions.
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    So it's kind of charming that,
    in terms of your personal expenditure,
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    you stay at the level you were at before.
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    That's societally quite appropriate.
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    But on your giving, you need to scale up
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    or else it will be your will,
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    and you won't get to shape it
    and enjoy it quite that same way.
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    And so without,
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    we don't want to mandate it,
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    but yes, both you and I
    want to inspire philanthropists
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    to see that passion,
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    to see those opportunities,
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    significantly faster than in the past,
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    because whether it's race or disease
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    or all the other social ills,
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    the innovation of what philanthropy
    can go to and do quickly
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    that, if it works, government
    can come in behind it and scale it up,
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    God knows we need solutions,
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    we need that kind of hope and progress
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    that expectations are high
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    that will solve very tough problems.
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    CA: I mean, most philanthropists,
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    even the best of them,
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    find it hard to give away more than about
    a percent of their net worth every year,
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    and yet the world's richest
    often have access
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    to great investment opportunities.
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    Many of them are gaining wealth
    at seven to 10 percent plus per year.
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    Isn't it the case that
    to have a real chance
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    of giving away half your fortune,
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    at some point you have to plan
    to give away five, six, seven, eight,
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    10 percent of your net worth annually?
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    And that is, isn't that the logic
    of what should be happening?
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    BG: Yeah, there are people
    like Chuck Feeney,
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    who set a good example
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    and gave away all of his money.
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    Even Melinda and I are talking about,
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    should we up the rate that we give at?
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    As you say, we've been very lucky
    on the investment side
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    through a variety of things.
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    Tech fortunes in general have done well,
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    even this year,
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    which is one of those great contrasts
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    in what's going on in the world.
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    And I do think there's an expectation
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    that we should speed up,
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    and there's a reason to speed up,
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    and government is going
    to miss a lot of needs.
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    Yes, there's tons of government
    money out there,
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    but helping it be spent well,
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    helping find places it's not stepping up,
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    and if people are willing to give
    to the developing world,
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    they don't have governments
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    that can print checks
    for 15 percent of GDP,
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    and so the suffering there broadly,
    just the economic stuff alone,
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    put aside the pandemic,
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    is tragic.
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    It's about a five year setback
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    in terms of these countries
    moving forward,
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    and in a few cases it's tough enough
    that the very stability of the country
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    is in question.
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    CA: Well, Bill,
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    I'm in awe of what you
    and Melinda have done.
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    You walk this narrow path
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    of trying to juggle
    so many different things,
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    and the amount of time that you dedicate
    to the betterment of the world at large,
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    and definitely the amount of money
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    and the amount of passion you put into it,
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    I mean, it's pretty awesome,
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    and I'm really grateful to you
    for spending this time with us now.
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    Thank you so much,
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    and honestly the rest of this year
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    your skills and resources
    are going to be needed more than ever,
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    so good luck.
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    BG: Well, thanks.
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    It's fun work and I'm optimistic,
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    so thanks, Chris.
Title:
How the pandemic will shape the near future
Speaker:
Bill Gates
Description:

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Video Language:
English
Team:
closed TED
Project:
TEDTalks
Duration:
43:07

English subtitles

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