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Format: Layer, Start, End, Style, Name, MarginL, MarginR, MarginV, Effect, Text
Dialogue: 0,0:00:00.00,0:00:02.00,Default,,0000,0000,0000,,One way to change our genes is to make new ones,
Dialogue: 0,0:00:02.00,0:00:04.00,Default,,0000,0000,0000,,as Craig Venter has so elegantly shown.
Dialogue: 0,0:00:04.00,0:00:07.00,Default,,0000,0000,0000,,Another is to change our lifestyles.
Dialogue: 0,0:00:07.00,0:00:11.00,Default,,0000,0000,0000,,And what we're learning is how powerful and dynamic these changes can be,
Dialogue: 0,0:00:11.00,0:00:14.00,Default,,0000,0000,0000,,that you don't have to wait very long to see the benefits.
Dialogue: 0,0:00:14.00,0:00:19.00,Default,,0000,0000,0000,,When you eat healthier, manage stress, exercise and love more,
Dialogue: 0,0:00:19.00,0:00:21.00,Default,,0000,0000,0000,,your brain actually gets more blood flow and more oxygen.
Dialogue: 0,0:00:21.00,0:00:24.00,Default,,0000,0000,0000,,But more than that, your brain gets measurably bigger.
Dialogue: 0,0:00:24.00,0:00:26.00,Default,,0000,0000,0000,,Things that were thought impossible just a few years ago
Dialogue: 0,0:00:26.00,0:00:28.00,Default,,0000,0000,0000,,can actually be measured now.
Dialogue: 0,0:00:28.00,0:00:31.00,Default,,0000,0000,0000,,This was figured out by Robin Williams
Dialogue: 0,0:00:31.00,0:00:33.00,Default,,0000,0000,0000,,a few years before the rest of us.
Dialogue: 0,0:00:33.00,0:00:35.00,Default,,0000,0000,0000,,Now, there's some things that you can do
Dialogue: 0,0:00:35.00,0:00:38.00,Default,,0000,0000,0000,,to make your brain grow new brain cells.
Dialogue: 0,0:00:38.00,0:00:40.00,Default,,0000,0000,0000,,Some of my favorite things, like chocolate and tea, blueberries,
Dialogue: 0,0:00:40.00,0:00:44.00,Default,,0000,0000,0000,,alcohol in moderation, stress management
Dialogue: 0,0:00:44.00,0:00:46.00,Default,,0000,0000,0000,,and cannabinoids found in marijuana.
Dialogue: 0,0:00:46.00,0:00:48.00,Default,,0000,0000,0000,,I'm just the messenger.
Dialogue: 0,0:00:49.00,0:00:52.00,Default,,0000,0000,0000,,(Laughter)
Dialogue: 0,0:00:52.00,0:00:55.00,Default,,0000,0000,0000,,What were we just talking about?
Dialogue: 0,0:00:55.00,0:00:57.00,Default,,0000,0000,0000,,(Laughter)
Dialogue: 0,0:00:57.00,0:00:59.00,Default,,0000,0000,0000,,And other things that can make it worse,
Dialogue: 0,0:00:59.00,0:01:01.00,Default,,0000,0000,0000,,that can cause you to lose brain cells.
Dialogue: 0,0:01:01.00,0:01:04.00,Default,,0000,0000,0000,,The usual suspects, like saturated fat and sugar,
Dialogue: 0,0:01:04.00,0:01:08.00,Default,,0000,0000,0000,,nicotine, opiates, cocaine, too much alcohol and chronic stress.
Dialogue: 0,0:01:08.00,0:01:11.00,Default,,0000,0000,0000,,Your skin gets more blood flow when you change your lifestyle,
Dialogue: 0,0:01:11.00,0:01:14.00,Default,,0000,0000,0000,,so you age less quickly. Your skin doesn't wrinkle as much.
Dialogue: 0,0:01:14.00,0:01:16.00,Default,,0000,0000,0000,,Your heart gets more blood flow.
Dialogue: 0,0:01:16.00,0:01:18.00,Default,,0000,0000,0000,,We've shown that you can actually reverse heart disease.
Dialogue: 0,0:01:18.00,0:01:21.00,Default,,0000,0000,0000,,That these clogged arteries that you see on the upper left,
Dialogue: 0,0:01:21.00,0:01:23.00,Default,,0000,0000,0000,,after only a year become measurably less clogged.
Dialogue: 0,0:01:23.00,0:01:25.00,Default,,0000,0000,0000,,And the cardiac PET scan shown on the lower left,
Dialogue: 0,0:01:25.00,0:01:27.00,Default,,0000,0000,0000,,the blue means no blood flow.
Dialogue: 0,0:01:27.00,0:01:30.00,Default,,0000,0000,0000,,A year later -- orange and white is maximum blood flow.
Dialogue: 0,0:01:30.00,0:01:33.00,Default,,0000,0000,0000,,We've shown you may be able to stop and reverse the progression
Dialogue: 0,0:01:33.00,0:01:35.00,Default,,0000,0000,0000,,of early prostate cancer and, by extension, breast cancer,
Dialogue: 0,0:01:35.00,0:01:37.00,Default,,0000,0000,0000,,simply by making these changes.
Dialogue: 0,0:01:37.00,0:01:40.00,Default,,0000,0000,0000,,We've found that tumor growth in vitro was inhibited
Dialogue: 0,0:01:40.00,0:01:42.00,Default,,0000,0000,0000,,70 percent in the group that made these changes,
Dialogue: 0,0:01:42.00,0:01:45.00,Default,,0000,0000,0000,,whereas only nine percent in the comparison group.
Dialogue: 0,0:01:45.00,0:01:47.00,Default,,0000,0000,0000,,These differences were highly significant.
Dialogue: 0,0:01:47.00,0:01:49.00,Default,,0000,0000,0000,,Even your sexual organs get more blood flow,
Dialogue: 0,0:01:49.00,0:01:51.00,Default,,0000,0000,0000,,so you increase sexual potency.
Dialogue: 0,0:01:51.00,0:01:53.00,Default,,0000,0000,0000,,One of the most effective anti-smoking ads was done
Dialogue: 0,0:01:53.00,0:01:55.00,Default,,0000,0000,0000,,by the Department of Health Services,
Dialogue: 0,0:01:55.00,0:01:57.00,Default,,0000,0000,0000,,showing that nicotine, which constricts your arteries,
Dialogue: 0,0:01:57.00,0:01:59.00,Default,,0000,0000,0000,,can cause a heart attack or a stroke,
Dialogue: 0,0:01:59.00,0:02:01.00,Default,,0000,0000,0000,,but it also causes impotence.
Dialogue: 0,0:02:01.00,0:02:03.00,Default,,0000,0000,0000,,Half of guys who smoke are impotent.
Dialogue: 0,0:02:03.00,0:02:04.00,Default,,0000,0000,0000,,How sexy is that?
Dialogue: 0,0:02:04.00,0:02:06.00,Default,,0000,0000,0000,,Now we're also about to publish a study --
Dialogue: 0,0:02:06.00,0:02:09.00,Default,,0000,0000,0000,,the first study showing you can change gene expression in men with prostate cancer.
Dialogue: 0,0:02:09.00,0:02:11.00,Default,,0000,0000,0000,,This is what's called a heat map --
Dialogue: 0,0:02:11.00,0:02:14.00,Default,,0000,0000,0000,,and the different colors -- and along the side, on the right, are different genes.
Dialogue: 0,0:02:14.00,0:02:17.00,Default,,0000,0000,0000,,And we found that over 500 genes were favorably changed --
Dialogue: 0,0:02:17.00,0:02:20.00,Default,,0000,0000,0000,,in effect, turning on the good genes, the disease-preventing genes,
Dialogue: 0,0:02:20.00,0:02:24.00,Default,,0000,0000,0000,,turning off the disease-promoting genes.
Dialogue: 0,0:02:24.00,0:02:27.00,Default,,0000,0000,0000,,And so these findings I think are really very powerful,
Dialogue: 0,0:02:27.00,0:02:29.00,Default,,0000,0000,0000,,giving many people new hope and new choices.
Dialogue: 0,0:02:29.00,0:02:34.00,Default,,0000,0000,0000,,And companies like Navigenics and DNA Direct and 23andMe,
Dialogue: 0,0:02:34.00,0:02:37.00,Default,,0000,0000,0000,,that are giving you your genetic profiles,
Dialogue: 0,0:02:37.00,0:02:40.00,Default,,0000,0000,0000,,are giving some people a sense of, "Gosh, well, what can I do about it?"
Dialogue: 0,0:02:40.00,0:02:43.00,Default,,0000,0000,0000,,Well, our genes are not our fate, and if we make these changes --
Dialogue: 0,0:02:43.00,0:02:45.00,Default,,0000,0000,0000,,they're a predisposition -- but if we make bigger changes
Dialogue: 0,0:02:45.00,0:02:47.00,Default,,0000,0000,0000,,than we might have made otherwise,
Dialogue: 0,0:02:47.00,0:02:50.00,Default,,0000,0000,0000,,we can actually change how our genes are expressed.
Dialogue: 0,0:02:50.00,0:02:51.00,Default,,0000,0000,0000,,Thank you.
Dialogue: 0,0:02:51.00,0:02:53.00,Default,,0000,0000,0000,,(Applause)