WEBVTT

00:00:06.539 --> 00:00:09.450
Buvingiz sizni yoshligidagi jasurligi 
bilan lol qoldirsa ham,

00:00:09.450 --> 00:00:13.364
siz buvingiz trapez ustasi bo'lganiga
ishonishingiz qiyin bo'lsa kerak.

00:00:13.364 --> 00:00:18.344
Ammo bel va tirsakdagi og'rig', qariyalar
orasida keng tarqalgan tizza qirsillashi

00:00:18.344 --> 00:00:20.497
shunchaki “qarilik” emas.

00:00:20.497 --> 00:00:25.157
Aslida, bog'imdagi qotish holati 
ko'plab yoshlarni ham azoblantiradi.

00:00:25.157 --> 00:00:26.838
Sabachisi artrit.

00:00:26.838 --> 00:00:29.974
Bu kasallik bo’g’imlarda yallig’lanish va
og’riq keltiradi.

00:00:29.974 --> 00:00:33.694
AQShda 90 million kishilarda mavjud.

00:00:33.694 --> 00:00:36.567
Ammo qotgan va qirsillaydigan 
bo'g'imlar muqarrar holatmi?

00:00:36.567 --> 00:00:38.781
Nima sababdan artrit 
ko'p uchraydiga kasallik

00:00:38.781 --> 00:00:42.619
va nima uchun haligacha bu keng 
tarqalgan kasallikga da'vo topmadik?

NOTE Paragraph

00:00:42.619 --> 00:00:45.538
Birinchi to'siq bu artritning

00:00:45.538 --> 00:00:48.949
yuzta turli hil holatlardan iboratligi.

00:00:48.949 --> 00:00:53.103
Bu barcha holatlarda bo'gimda og'riq hamda
yallig'lanish kuzatiladi.

00:00:53.103 --> 00:00:57.120
Ammo, bularni nima keltirishi hamda
simptomlar avjligi farqlanadi.

NOTE Paragraph

00:00:57.120 --> 00:00:59.812
Hattoki, eng tarqalgan turi osteoartritni

00:00:59.812 --> 00:01:02.217
oldini olish biz oylagandek oson emas.

00:01:02.217 --> 00:01:06.242
Artrit aynan bir yosh guruhiga 
munosibligi notog'ri tushunchadir.

00:01:06.242 --> 00:01:10.640
Osteoartrit sababi ko'pincha
bemorning yoshligidagi

00:01:10.640 --> 00:01:13.681
oddiy jarohat tufayli yuzaga kelgani
aniqlanishi mumkin.

00:01:13.681 --> 00:01:18.211
Immunitet hujayralari tezda shikastlangan
joyni tozalash va tiklashga yordam berib,

00:01:18.211 --> 00:01:20.001
fermentlarni ishlab chiqaradi.

00:01:20.001 --> 00:01:24.065
Bu fermentlardan bir turlari bu matritca 
metalloproteinazlari va agrekanazlaridir.

00:01:24.065 --> 00:01:28.221
Bular shikastlangan joydagi toqimalarni 
tozalaydi va yallig'lanishni qozg'atadi.

00:01:28.221 --> 00:01:31.545
Tez shishish tizza bog'imining
tiklanish vaqtida himoya qilsa ham,

00:01:31.545 --> 00:01:36.215
lekin toqimar to'liq bitmasa immunitet
hujayralari vaqtdan ortiq qolib ketadi.

00:01:36.215 --> 00:01:39.741
Fermentlar to'htamay ishlab chiqarilishi
to'g'ayni yemiradi,

00:01:39.741 --> 00:01:43.133
bo'g'imni kuchsizlantiradi, va artrit 
holatini yaratadi.

NOTE Paragraph

00:01:43.133 --> 00:01:47.813
Artritning barcha turlari o'tmishdagi
sport shikasti tufayli emasdir.

00:01:47.813 --> 00:01:52.583
AQShda 1, 3 million kishida uchraydigan 
romatoid artritini misol qilib olamiz.

00:01:52.583 --> 00:01:55.247
Bu kasallik aslida autoimmun kasalligidir,

00:01:55.247 --> 00:01:58.855
autoantitanalar tabiiy holda ishlab 
chiqariladigan oqsillarga hujum qiladi.

00:01:58.855 --> 00:02:01.874
Bu oqsillardan bir turini bog'im tog'ayi
ishlab chiqaradi.

00:02:01.874 --> 00:02:04.114
Bunga sababchi nima ekanligi
hali ham no'malum.

00:02:04.114 --> 00:02:08.195
Ammo, hulosa shuki organizm bog'im 
toqimasini horijiy bosqinchi deb ko'radi.

00:02:08.195 --> 00:02:13.245
Immunitet hujayralari toqimani sozlashga
hojat bo'lmasa ham bostirib kiradi.

00:02:13.245 --> 00:02:15.984
Bu reaktciya surunkali yallig'lanishga
olib borib,

00:02:15.984 --> 00:02:18.893
suyak va to'g'ayni yemiradi.

NOTE Paragraph

00:02:18.893 --> 00:02:21.648
Yana bitta kassalik turi, 
spondiloartrit,

00:02:21.648 --> 00:02:24.711
bu paytgacha etib otilgan kasalliklarga
o'hshash joylari bor.

00:02:24.711 --> 00:02:27.766
Bemorlar bog'imlarida doimiy 
yallig'lanish kuzatiladi,

00:02:27.766 --> 00:02:30.909
Bu holat pay va chandirlar suyakka 
qoshiladigan, hattoki avval

00:02:30.909 --> 00:02:33.265
shikast yetqazilmagan joylarda
ham kuzatiladi.

00:02:33.265 --> 00:02:37.835
Fermentlar toshib kelib, osteoartritdagi 
yemirilish holatiga oboradi.

00:02:37.835 --> 00:02:42.027
Ammo, buni sababchisi 
sitokin oqsillari bo'ladi.

00:02:42.027 --> 00:02:44.363
Fermentlar to'g'ayni yemirgani sari,

00:02:44.363 --> 00:02:48.409
organizm kichik bo'g'imlarni qo'shib 
ularni barqarorlashtirishga urinadi.

00:02:48.409 --> 00:02:52.548
Bu jarayon paytida ba'zan suyak shporalari
deb ataladigan o'simtalar paydo bo'ladi,

00:02:52.548 --> 00:02:56.023
bu o'simtalar kuchli bo'g'im og'rig'i va
zichlanishiga sabab bo'ladi.

NOTE Paragraph

00:02:56.023 --> 00:02:58.296
Artrit kasalligini keltiradigan 
omillar ko'p.

00:02:58.296 --> 00:03:01.405
Shu bois hozirda faqat 
alomatlarni da'volash usullari qollanadi,

00:03:01.405 --> 00:03:03.405
kasallik sababchilarini emas.

00:03:03.405 --> 00:03:05.839
Bu usullarning biri МАТХ metodi bo'lib,

00:03:05.839 --> 00:03:09.928
to'g'ayning bo'laklaridan hujayralar 
to'planib, ulardan yangi toqima yasaladi.

00:03:09.928 --> 00:03:12.267
Boshqa bitta usul bu mikrofraktura.

00:03:12.267 --> 00:03:14.772
Hirurglar kickik teshiklar yaratib,
ular orqali

00:03:14.772 --> 00:03:19.182
suyak iligidan ildiz hujayralari 
oqib chiqib yangi to'g'ay yaratadi.

00:03:19.182 --> 00:03:20.332
Eng ohorgi chora

00:03:20.332 --> 00:03:24.832
to'g'ayi butunlay yemirilgan bemorning
toliq bo'g'imini almashtiriluvi.

NOTE Paragraph

00:03:24.832 --> 00:03:26.663
Ammo bu kabi keskin choralar
bo'lsa ham

00:03:26.663 --> 00:03:29.425
autoimmun artritni yaratuvchi sabablarini

00:03:29.425 --> 00:03:32.441
da'volash hali ham mushkul masaladir.

00:03:32.441 --> 00:03:36.828
Olimlar NOF-alfa oqsil terapiya usullarini
qollab oldinga ketayaptilar.

00:03:36.828 --> 00:03:40.847
Bu oqsil romatid artrit yallig'lanishing 
asosiy sababchilaridar biridir.

00:03:40.847 --> 00:03:46.017
Ammo, bu usul ham kasallik sababini emas,
kasallik alomatlarini da'volaydi holos.

NOTE Paragraph

00:03:46.017 --> 00:03:51.509
Bu orada esa, artrit oldini olishning eng 
yanhshi himoyasi bu hayot tarzidir, misol

00:03:51.509 --> 00:03:54.538
sog'lom vazn ushlash, bu bo'g'imlarga 
bosimni tushiradi, yoki

00:03:54.538 --> 00:03:59.258
yoga va velosiped minish kabi oson 
mashq'ulotlar bajarish, va chekmaslik.

00:03:59.258 --> 00:04:03.192
Bu kabi artrit oldini oladigan faoliyatlar
uzoq umr kechirishimizga yordam beradi.

00:04:03.192 --> 00:04:06.092
Bizlar turli hil artrit kasalliklarini 
da'volash yollarini

00:04:06.092 --> 00:04:09.102
tadqiqot yoli bilan izlashni 
davom etamiz.