[Script Info]
Title: 
[Events]
Format: Layer, Start, End, Style, Name, MarginL, MarginR, MarginV, Effect, Text
Dialogue: 0,0:00:00.74,0:00:02.38,Default,,0000,0000,0000,,San.
Dialogue: 0,0:00:02.38,0:00:05.20,Default,,0000,0000,0000,,U njemu provedemo oko trećine života,
Dialogue: 0,0:00:05.20,0:00:08.52,Default,,0000,0000,0000,,ali da li iko razume\No čemu se tu zapravo radi?
Dialogue: 0,0:00:08.52,0:00:10.74,Default,,0000,0000,0000,,Galen, jedan od najznačajnijih lekara
Dialogue: 0,0:00:10.74,0:00:12.88,Default,,0000,0000,0000,,starog veka je pre 2.000 godina
Dialogue: 0,0:00:12.88,0:00:13.94,Default,,0000,0000,0000,,pretpostavio da se
Dialogue: 0,0:00:13.94,0:00:16.26,Default,,0000,0000,0000,,pokretačka sila našeg mozga,
Dialogue: 0,0:00:16.26,0:00:19.62,Default,,0000,0000,0000,,njegovo gorivo, dok smo budni
Dialogue: 0,0:00:19.62,0:00:22.19,Default,,0000,0000,0000,,sliva u ostatak tela
Dialogue: 0,0:00:22.19,0:00:26.20,Default,,0000,0000,0000,,i oživljava ga, ali isušuje mozak,
Dialogue: 0,0:00:26.20,0:00:27.82,Default,,0000,0000,0000,,a dok spavamo,
Dialogue: 0,0:00:27.82,0:00:30.36,Default,,0000,0000,0000,,sva ta vlaga iz ostatka tela
Dialogue: 0,0:00:30.36,0:00:32.10,Default,,0000,0000,0000,,se vraća,
Dialogue: 0,0:00:32.10,0:00:33.91,Default,,0000,0000,0000,,vlaži mozak
Dialogue: 0,0:00:33.91,0:00:36.46,Default,,0000,0000,0000,,i osvežava um.
Dialogue: 0,0:00:36.46,0:00:38.88,Default,,0000,0000,0000,,Sada nam to zvuči kao budalaština,
Dialogue: 0,0:00:38.88,0:00:40.92,Default,,0000,0000,0000,,ali to je bio Galenov pokušaj da objasni
Dialogue: 0,0:00:40.92,0:00:42.53,Default,,0000,0000,0000,,jednu od odlika sna
Dialogue: 0,0:00:42.53,0:00:45.18,Default,,0000,0000,0000,,sa kojom se svakodnevno susrećemo.
Dialogue: 0,0:00:45.18,0:00:47.11,Default,,0000,0000,0000,,Svi iz iskustva znamo
Dialogue: 0,0:00:47.11,0:00:49.82,Default,,0000,0000,0000,,da san bistri um,
Dialogue: 0,0:00:49.82,0:00:51.28,Default,,0000,0000,0000,,ali u nedostatku sna,
Dialogue: 0,0:00:51.28,0:00:54.21,Default,,0000,0000,0000,,on se usporava.
Dialogue: 0,0:00:54.21,0:00:56.72,Default,,0000,0000,0000,,Iako se sad zna mnogo više o snu
Dialogue: 0,0:00:56.72,0:00:58.53,Default,,0000,0000,0000,,nego u Galenovo vreme,
Dialogue: 0,0:00:58.53,0:01:01.41,Default,,0000,0000,0000,,još uvek ne znamo zbog čega
Dialogue: 0,0:01:01.41,0:01:04.04,Default,,0000,0000,0000,,od svih aktivnosti, baš san
Dialogue: 0,0:01:04.04,0:01:06.75,Default,,0000,0000,0000,,tako uspešno obnavlja um.
Dialogue: 0,0:01:06.75,0:01:08.25,Default,,0000,0000,0000,,Danas ću vam pričati o nekim
Dialogue: 0,0:01:08.25,0:01:09.61,Default,,0000,0000,0000,,skorijim istraživanjima
Dialogue: 0,0:01:09.61,0:01:12.37,Default,,0000,0000,0000,,koje prikazuju ovo pitanje u novom svetlu.
Dialogue: 0,0:01:12.37,0:01:15.57,Default,,0000,0000,0000,,Otkrili smo da je san
Dialogue: 0,0:01:15.57,0:01:17.95,Default,,0000,0000,0000,,možda elegantan odgovor
Dialogue: 0,0:01:17.95,0:01:20.52,Default,,0000,0000,0000,,na neke od osnovnih potreba mozga,
Dialogue: 0,0:01:20.52,0:01:22.47,Default,,0000,0000,0000,,jedinstven način na koji mozak
Dialogue: 0,0:01:22.47,0:01:25.29,Default,,0000,0000,0000,,sa malo grešaka ispunjava teške zahteve
Dialogue: 0,0:01:25.29,0:01:30.29,Default,,0000,0000,0000,,i koji ga odvaja od ostalih organa.
Dialogue: 0,0:01:30.29,0:01:33.35,Default,,0000,0000,0000,,Gotovo celokupna biologija
Dialogue: 0,0:01:33.35,0:01:35.80,Default,,0000,0000,0000,,može da se posmatra kao niz problema
Dialogue: 0,0:01:35.80,0:01:37.84,Default,,0000,0000,0000,,i odgovarajućih rešenja,
Dialogue: 0,0:01:37.84,0:01:41.32,Default,,0000,0000,0000,,a prvi problem\Nkoji svaki organ mora da reši
Dialogue: 0,0:01:41.32,0:01:43.82,Default,,0000,0000,0000,,je neprekidna dostava hranljivih materija
Dialogue: 0,0:01:43.82,0:01:45.56,Default,,0000,0000,0000,,koje napajaju ćelije tela.
Dialogue: 0,0:01:45.56,0:01:48.14,Default,,0000,0000,0000,,Za mozak je to naročito važno;
Dialogue: 0,0:01:48.14,0:01:50.36,Default,,0000,0000,0000,,njegova intenzivna električna aktivnost
Dialogue: 0,0:01:50.36,0:01:53.21,Default,,0000,0000,0000,,troši četvrtinu energije tela,
Dialogue: 0,0:01:53.21,0:01:54.84,Default,,0000,0000,0000,,iako mozak čini
Dialogue: 0,0:01:54.84,0:01:58.18,Default,,0000,0000,0000,,svega dva procenta telesne mase.
Dialogue: 0,0:01:58.18,0:01:59.79,Default,,0000,0000,0000,,Zbog toga krvotok rešava
Dialogue: 0,0:01:59.79,0:02:02.22,Default,,0000,0000,0000,,problem dostave hranljivih materija
Dialogue: 0,0:02:02.22,0:02:04.76,Default,,0000,0000,0000,,tako što krvnim sudovima šalje
Dialogue: 0,0:02:04.76,0:02:08.11,Default,,0000,0000,0000,,hranljive materije\Ni kiseonik u čitavo telo.
Dialogue: 0,0:02:08.11,0:02:11.12,Default,,0000,0000,0000,,Na ovom snimku se to i vidi.
Dialogue: 0,0:02:11.12,0:02:12.70,Default,,0000,0000,0000,,Prikazani su krvni sudovi
Dialogue: 0,0:02:12.70,0:02:15.60,Default,,0000,0000,0000,,u mozgu živog miša.
Dialogue: 0,0:02:15.60,0:02:18.12,Default,,0000,0000,0000,,Krvni sudovi čine složenu mrežu
Dialogue: 0,0:02:18.12,0:02:20.46,Default,,0000,0000,0000,,koja prožima čitavu zapreminu mozga.
Dialogue: 0,0:02:20.46,0:02:22.27,Default,,0000,0000,0000,,Kreću na površini mozga,
Dialogue: 0,0:02:22.27,0:02:25.15,Default,,0000,0000,0000,,a zatim se spuštaju u samo tkivo
Dialogue: 0,0:02:25.15,0:02:27.51,Default,,0000,0000,0000,,i čitavim putem u svaku ćeliju mozga
Dialogue: 0,0:02:27.51,0:02:33.27,Default,,0000,0000,0000,,dostavljaju hranljive materije i kiseonik.
Dialogue: 0,0:02:33.28,0:02:36.25,Default,,0000,0000,0000,,Kao što svakoj ćeliji
Dialogue: 0,0:02:36.25,0:02:38.14,Default,,0000,0000,0000,,trebaju hranljive materije,
Dialogue: 0,0:02:38.14,0:02:41.28,Default,,0000,0000,0000,,tako i svaka proizvodi otpadne materije,
Dialogue: 0,0:02:41.28,0:02:42.82,Default,,0000,0000,0000,,a čišćenje tog otpada
Dialogue: 0,0:02:42.82,0:02:45.09,Default,,0000,0000,0000,,je drugi problem
Dialogue: 0,0:02:45.09,0:02:47.88,Default,,0000,0000,0000,,koji svaki organ mora da reši.
Dialogue: 0,0:02:47.88,0:02:50.46,Default,,0000,0000,0000,,Ovaj dijagram prikazuje limfni sistem
Dialogue: 0,0:02:50.46,0:02:52.90,Default,,0000,0000,0000,,koji se razvio da bi ispunio tu potrebu.
Dialogue: 0,0:02:52.90,0:02:55.71,Default,,0000,0000,0000,,Paralelan je u odnosu na krvotok,
Dialogue: 0,0:02:55.71,0:02:57.72,Default,,0000,0000,0000,,i on prožima čitavo telo.
Dialogue: 0,0:02:57.72,0:02:59.68,Default,,0000,0000,0000,,Sakuplja proteine i ostali otpad
Dialogue: 0,0:02:59.68,0:03:01.60,Default,,0000,0000,0000,,iz međućelijskog prostora,
Dialogue: 0,0:03:01.60,0:03:04.41,Default,,0000,0000,0000,,a zatim ga ubacuje u krv
Dialogue: 0,0:03:04.41,0:03:06.68,Default,,0000,0000,0000,,kako bi mogao da se odstrani.
Dialogue: 0,0:03:06.68,0:03:08.46,Default,,0000,0000,0000,,Ako se ovaj dijagram dobro pogleda,
Dialogue: 0,0:03:08.46,0:03:09.86,Default,,0000,0000,0000,,uočava se nešto
Dialogue: 0,0:03:09.86,0:03:12.19,Default,,0000,0000,0000,,što nema smisla.
Dialogue: 0,0:03:12.19,0:03:14.94,Default,,0000,0000,0000,,Ako mu uvećamo glavu,
Dialogue: 0,0:03:14.94,0:03:17.14,Default,,0000,0000,0000,,između ostalog se vidi
Dialogue: 0,0:03:17.14,0:03:21.30,Default,,0000,0000,0000,,da u mozgu nema limfnih sudova.
Dialogue: 0,0:03:21.30,0:03:24.39,Default,,0000,0000,0000,,Ali to baš i nema smisla, zar ne?
Dialogue: 0,0:03:24.39,0:03:27.60,Default,,0000,0000,0000,,Mozak je ipak vrlo aktivan organ
Dialogue: 0,0:03:27.60,0:03:30.16,Default,,0000,0000,0000,,i shodno tome proizvodi dosta otpada
Dialogue: 0,0:03:30.16,0:03:32.74,Default,,0000,0000,0000,,koji mora da se ukloni.
Dialogue: 0,0:03:32.74,0:03:35.70,Default,,0000,0000,0000,,Ali ipak nema limfne sudove, što znači
Dialogue: 0,0:03:35.70,0:03:37.50,Default,,0000,0000,0000,,da način na koji ostatak tela
Dialogue: 0,0:03:37.50,0:03:39.48,Default,,0000,0000,0000,,uklanja otpad
Dialogue: 0,0:03:39.48,0:03:42.49,Default,,0000,0000,0000,,kod mozga ne radi.
Dialogue: 0,0:03:42.49,0:03:44.54,Default,,0000,0000,0000,,Kako onda mozak rešava
Dialogue: 0,0:03:44.54,0:03:46.29,Default,,0000,0000,0000,,problem uklanjanja otpada?
Dialogue: 0,0:03:46.29,0:03:49.98,Default,,0000,0000,0000,,Kod ovog naizgled običnog pitanja
Dialogue: 0,0:03:49.98,0:03:53.39,Default,,0000,0000,0000,,se naša grupa prvi put uključila u priču
Dialogue: 0,0:03:53.39,0:03:55.41,Default,,0000,0000,0000,,i pronicanjem u mozak,
Dialogue: 0,0:03:55.41,0:03:57.75,Default,,0000,0000,0000,,u neurone i krvne sudove
Dialogue: 0,0:03:57.75,0:04:00.64,Default,,0000,0000,0000,,smo otkrili
Dialogue: 0,0:04:00.64,0:04:02.82,Default,,0000,0000,0000,,da mozak
Dialogue: 0,0:04:02.82,0:04:05.38,Default,,0000,0000,0000,,problem uklanjanja otpada
Dialogue: 0,0:04:05.38,0:04:07.20,Default,,0000,0000,0000,,rešava na neočekivan način.
Dialogue: 0,0:04:07.20,0:04:10.05,Default,,0000,0000,0000,,Istovremeno je
Dialogue: 0,0:04:10.05,0:04:13.17,Default,,0000,0000,0000,,i genijalno i prelepo.
Dialogue: 0,0:04:13.17,0:04:14.84,Default,,0000,0000,0000,,Reći ću vam šta smo otkrili.
Dialogue: 0,0:04:14.84,0:04:17.39,Default,,0000,0000,0000,,U mozgu postoji velika količina
Dialogue: 0,0:04:17.39,0:04:20.85,Default,,0000,0000,0000,,čiste, prozirne tečnosti\Nzvane moždano-moždinska tečnost.
Dialogue: 0,0:04:20.85,0:04:22.17,Default,,0000,0000,0000,,Zvaćemo je CSF.
Dialogue: 0,0:04:22.17,0:04:26.15,Default,,0000,0000,0000,,CSF ispunjava okolinu mozga,
Dialogue: 0,0:04:26.15,0:04:27.67,Default,,0000,0000,0000,,a otpad iz unutrašnjosti mozga
Dialogue: 0,0:04:27.67,0:04:29.89,Default,,0000,0000,0000,,prelazi CSF,
Dialogue: 0,0:04:29.89,0:04:33.16,Default,,0000,0000,0000,,i sa ostalim otpadom se ubacuje u krv.
Dialogue: 0,0:04:33.16,0:04:34.28,Default,,0000,0000,0000,,U tom pogledu
Dialogue: 0,0:04:34.28,0:04:36.87,Default,,0000,0000,0000,,dosta liči na limfni sistem, zar ne?
Dialogue: 0,0:04:36.87,0:04:39.62,Default,,0000,0000,0000,,Zanimljivo je to što tečnost
Dialogue: 0,0:04:39.62,0:04:41.36,Default,,0000,0000,0000,,i otpad iz mozga
Dialogue: 0,0:04:41.36,0:04:43.76,Default,,0000,0000,0000,,ne prelaze
Dialogue: 0,0:04:43.76,0:04:46.14,Default,,0000,0000,0000,,u CSF nasumice.
Dialogue: 0,0:04:46.14,0:04:49.86,Default,,0000,0000,0000,,Zapravo postoji\Nspecijalizovana mreža sudova
Dialogue: 0,0:04:49.86,0:04:53.75,Default,,0000,0000,0000,,koja to omogućava.
Dialogue: 0,0:04:53.75,0:04:55.90,Default,,0000,0000,0000,,Vidi se na ovom snimku.
Dialogue: 0,0:04:55.90,0:04:58.94,Default,,0000,0000,0000,,Tu je ponovo prikazan
Dialogue: 0,0:04:58.94,0:05:00.42,Default,,0000,0000,0000,,mozak živog miša.
Dialogue: 0,0:05:00.42,0:05:02.35,Default,,0000,0000,0000,,Sa leve strane je prikazano
Dialogue: 0,0:05:02.35,0:05:04.41,Default,,0000,0000,0000,,šta se dešava na površini mozga,
Dialogue: 0,0:05:04.41,0:05:05.97,Default,,0000,0000,0000,,a sa desne
Dialogue: 0,0:05:05.97,0:05:07.92,Default,,0000,0000,0000,,šta se dešava ispod površine,
Dialogue: 0,0:05:07.92,0:05:09.64,Default,,0000,0000,0000,,unutar samog tkiva.
Dialogue: 0,0:05:09.64,0:05:11.90,Default,,0000,0000,0000,,Krvni sudovi su obeleženi crvenom bojom,
Dialogue: 0,0:05:11.90,0:05:13.92,Default,,0000,0000,0000,,a CSF koji okružuje mozak
Dialogue: 0,0:05:13.92,0:05:15.74,Default,,0000,0000,0000,,je zelena.
Dialogue: 0,0:05:15.74,0:05:17.54,Default,,0000,0000,0000,,Iznenadilo nas je
Dialogue: 0,0:05:17.54,0:05:20.80,Default,,0000,0000,0000,,što tečnost koja okružuje mozak
Dialogue: 0,0:05:20.80,0:05:23.61,Default,,0000,0000,0000,,nije ostala van njega.
Dialogue: 0,0:05:23.61,0:05:27.01,Default,,0000,0000,0000,,CSF se ustvari vraćao unutar mozga
Dialogue: 0,0:05:27.01,0:05:28.88,Default,,0000,0000,0000,,i kretao se kroz njega
Dialogue: 0,0:05:28.88,0:05:31.92,Default,,0000,0000,0000,,duž spoljne strane krvnih sudova,
Dialogue: 0,0:05:31.92,0:05:34.30,Default,,0000,0000,0000,,i tokom tog kretanja
Dialogue: 0,0:05:34.30,0:05:36.10,Default,,0000,0000,0000,,je zapravo pomagao
Dialogue: 0,0:05:36.10,0:05:38.91,Default,,0000,0000,0000,,u čišćenju otpada
Dialogue: 0,0:05:38.91,0:05:41.35,Default,,0000,0000,0000,,iz prostora između
Dialogue: 0,0:05:41.35,0:05:44.20,Default,,0000,0000,0000,,moždanih ćelija.
Dialogue: 0,0:05:44.20,0:05:46.11,Default,,0000,0000,0000,,Korišćenje spoljašnjosti
Dialogue: 0,0:05:46.11,0:05:49.59,Default,,0000,0000,0000,,krvnih sudova je
Dialogue: 0,0:05:49.59,0:05:52.11,Default,,0000,0000,0000,,zapravo veoma dobro rešenje,
Dialogue: 0,0:05:52.11,0:05:54.83,Default,,0000,0000,0000,,pošto je mozak okružen
Dialogue: 0,0:05:54.83,0:05:56.65,Default,,0000,0000,0000,,čvrstom lobanjom
Dialogue: 0,0:05:56.65,0:05:58.76,Default,,0000,0000,0000,,i sasvim popunjen ćelijama,
Dialogue: 0,0:05:58.76,0:06:01.50,Default,,0000,0000,0000,,tako da u njemu nema prostora
Dialogue: 0,0:06:01.50,0:06:05.10,Default,,0000,0000,0000,,za dodatnu mrežu sudova\Nkao što je limfni sistem.
Dialogue: 0,0:06:05.10,0:06:06.36,Default,,0000,0000,0000,,Međutim, krvni sudovi
Dialogue: 0,0:06:06.36,0:06:08.32,Default,,0000,0000,0000,,dosežu od površine mozga
Dialogue: 0,0:06:08.32,0:06:10.93,Default,,0000,0000,0000,,do svake ćelije,
Dialogue: 0,0:06:10.93,0:06:12.16,Default,,0000,0000,0000,,što znači da tečnost
Dialogue: 0,0:06:12.16,0:06:15.46,Default,,0000,0000,0000,,koja se kreće duž njih
Dialogue: 0,0:06:15.46,0:06:19.26,Default,,0000,0000,0000,,može da prodre u čitavu zapreminu mozga
Dialogue: 0,0:06:19.26,0:06:21.44,Default,,0000,0000,0000,,i to predstavlja veoma dobar način
Dialogue: 0,0:06:21.44,0:06:25.21,Default,,0000,0000,0000,,da mreža krvnih sudova
Dialogue: 0,0:06:25.21,0:06:27.100,Default,,0000,0000,0000,,preuzme ulogu druge mreže,
Dialogue: 0,0:06:27.100,0:06:31.18,Default,,0000,0000,0000,,limfnog sistema,
Dialogue: 0,0:06:31.18,0:06:33.59,Default,,0000,0000,0000,,i učini je nepotrebnom.
Dialogue: 0,0:06:33.59,0:06:35.91,Default,,0000,0000,0000,,Neverovatno je to da ni jedan drugi organ
Dialogue: 0,0:06:35.91,0:06:37.55,Default,,0000,0000,0000,,ne pristupa uklanjanju otpada
Dialogue: 0,0:06:37.55,0:06:40.61,Default,,0000,0000,0000,,na ovakav način.
Dialogue: 0,0:06:40.61,0:06:46.43,Default,,0000,0000,0000,,Ovo rešenje je jedinstveno za mozak.
Dialogue: 0,0:06:46.43,0:06:48.70,Default,,0000,0000,0000,,Ali smo se najviše iznenadili
Dialogue: 0,0:06:48.70,0:06:50.80,Default,,0000,0000,0000,,kad smo otkrili da se
Dialogue: 0,0:06:50.80,0:06:53.15,Default,,0000,0000,0000,,sve ovo o čemu sam pričao,
Dialogue: 0,0:06:53.15,0:06:56.47,Default,,0000,0000,0000,,tečnosti koje se kreću kroz mozak,
Dialogue: 0,0:06:56.47,0:07:00.65,Default,,0000,0000,0000,,dešava samo dok spavamo.
Dialogue: 0,0:07:00.65,0:07:02.10,Default,,0000,0000,0000,,Snimak sa leve strane
Dialogue: 0,0:07:02.10,0:07:04.36,Default,,0000,0000,0000,,prikazuje kretanje CSF
Dialogue: 0,0:07:04.36,0:07:07.97,Default,,0000,0000,0000,,u mozgu živog miša dok je budan.
Dialogue: 0,0:07:07.97,0:07:09.84,Default,,0000,0000,0000,,Skoro da ga i nema.
Dialogue: 0,0:07:09.84,0:07:11.42,Default,,0000,0000,0000,,Ali ako malo sačekamo
Dialogue: 0,0:07:11.42,0:07:14.62,Default,,0000,0000,0000,,da životinja zaspi
Dialogue: 0,0:07:14.62,0:07:17.38,Default,,0000,0000,0000,,vidimo kako CSF
Dialogue: 0,0:07:17.38,0:07:19.80,Default,,0000,0000,0000,,teče kroz mozak,
Dialogue: 0,0:07:19.80,0:07:21.96,Default,,0000,0000,0000,,a istovremeno se vidi
Dialogue: 0,0:07:21.96,0:07:24.57,Default,,0000,0000,0000,,da se ćelije smanjuju
Dialogue: 0,0:07:24.57,0:07:27.23,Default,,0000,0000,0000,,dok mozak spava,
Dialogue: 0,0:07:27.23,0:07:29.27,Default,,0000,0000,0000,,čime stvaraju međućelijski prostor
Dialogue: 0,0:07:29.27,0:07:31.41,Default,,0000,0000,0000,,i omogućavaju da
Dialogue: 0,0:07:31.41,0:07:34.14,Default,,0000,0000,0000,,tečnost prođe i ukloni otpad.
Dialogue: 0,0:07:34.14,0:07:36.65,Default,,0000,0000,0000,,Izgleda da Galen i nije
Dialogue: 0,0:07:36.65,0:07:38.91,Default,,0000,0000,0000,,mnogo pogrešio kad je pisao
Dialogue: 0,0:07:38.91,0:07:41.61,Default,,0000,0000,0000,,o tečnosti koja se kreće kroz mozak
Dialogue: 0,0:07:41.61,0:07:43.25,Default,,0000,0000,0000,,dok spavamo.
Dialogue: 0,0:07:43.25,0:07:46.32,Default,,0000,0000,0000,,Naše istraživanje,
Dialogue: 0,0:07:46.32,0:07:48.78,Default,,0000,0000,0000,,2.000 godina kasnije,
Dialogue: 0,0:07:48.78,0:07:50.83,Default,,0000,0000,0000,,pokazuje da mozak
Dialogue: 0,0:07:50.83,0:07:52.95,Default,,0000,0000,0000,,odlaže čišćenje otpada
Dialogue: 0,0:07:52.95,0:07:55.31,Default,,0000,0000,0000,,iz međućelijskog prostora
Dialogue: 0,0:07:55.31,0:07:58.38,Default,,0000,0000,0000,,dok je budan i zauzet,
Dialogue: 0,0:07:58.38,0:08:00.24,Default,,0000,0000,0000,,ali kad zaspi
Dialogue: 0,0:08:00.24,0:08:02.59,Default,,0000,0000,0000,,i ne mora više da radi,
Dialogue: 0,0:08:02.59,0:08:05.16,Default,,0000,0000,0000,,počinje da
Dialogue: 0,0:08:05.16,0:08:06.85,Default,,0000,0000,0000,,iz međućelijskog prostora
Dialogue: 0,0:08:06.85,0:08:08.36,Default,,0000,0000,0000,,čisti otpad
Dialogue: 0,0:08:08.36,0:08:10.78,Default,,0000,0000,0000,,koji se nagomilao u toku dana.
Dialogue: 0,0:08:10.78,0:08:13.18,Default,,0000,0000,0000,,Pomalo liči na to
Dialogue: 0,0:08:13.18,0:08:16.27,Default,,0000,0000,0000,,kako odlažemo kućne poslove\Ntokom radnih dana
Dialogue: 0,0:08:16.27,0:08:17.73,Default,,0000,0000,0000,,jer nemamo vremena,
Dialogue: 0,0:08:17.73,0:08:20.99,Default,,0000,0000,0000,,a onda moramo da nadoknadimo\Nsvo to čišćenje
Dialogue: 0,0:08:20.99,0:08:23.75,Default,,0000,0000,0000,,u toku vikenda.
Dialogue: 0,0:08:23.75,0:08:27.02,Default,,0000,0000,0000,,Dosta sam pričao o uklanjanju otpada,
Dialogue: 0,0:08:27.02,0:08:28.47,Default,,0000,0000,0000,,ali nisam ništa određeno rekao
Dialogue: 0,0:08:28.47,0:08:29.87,Default,,0000,0000,0000,,o vrsti otpada
Dialogue: 0,0:08:29.87,0:08:32.16,Default,,0000,0000,0000,,koji mozak mora da ukloni
Dialogue: 0,0:08:32.16,0:08:34.70,Default,,0000,0000,0000,,tokom sna kako bi ostao zdrav.
Dialogue: 0,0:08:34.70,0:08:36.30,Default,,0000,0000,0000,,Studije su pre svega posmatrale
Dialogue: 0,0:08:36.30,0:08:38.72,Default,,0000,0000,0000,,vrstu otpada zvanu amiloid-beta,
Dialogue: 0,0:08:38.72,0:08:41.91,Default,,0000,0000,0000,,koju čini protein\Nkog mozak stalno proizvodi.
Dialogue: 0,0:08:41.91,0:08:43.77,Default,,0000,0000,0000,,Moj mozak ga trenutno prozvodi,
Dialogue: 0,0:08:43.77,0:08:45.93,Default,,0000,0000,0000,,kao i vaš.
Dialogue: 0,0:08:45.93,0:08:47.93,Default,,0000,0000,0000,,Kod obolelih od Alchajmerove bolesti
Dialogue: 0,0:08:47.93,0:08:50.53,Default,,0000,0000,0000,,amiloid-beta se nagomilava
Dialogue: 0,0:08:50.53,0:08:52.54,Default,,0000,0000,0000,,u međućelijskom prostoru mozga
Dialogue: 0,0:08:52.54,0:08:55.97,Default,,0000,0000,0000,,umesto da se ukloni\Nkao što bi trebalo,
Dialogue: 0,0:08:55.97,0:08:57.98,Default,,0000,0000,0000,,te se smatra da je ovo nagomilavanje
Dialogue: 0,0:08:57.98,0:09:00.19,Default,,0000,0000,0000,,amiloid-bete jedan od ključnih koraka
Dialogue: 0,0:09:00.19,0:09:02.81,Default,,0000,0000,0000,,u razvoju ove strašne bolesti.
Dialogue: 0,0:09:02.81,0:09:05.91,Default,,0000,0000,0000,,Izmerili smo brzinu\Nuklanjanja amiloid-bete
Dialogue: 0,0:09:05.91,0:09:07.64,Default,,0000,0000,0000,,dok smo budni
Dialogue: 0,0:09:07.64,0:09:09.42,Default,,0000,0000,0000,,i dok spavamo
Dialogue: 0,0:09:09.42,0:09:11.30,Default,,0000,0000,0000,,i otkrili smo da je
Dialogue: 0,0:09:11.30,0:09:13.19,Default,,0000,0000,0000,,uklanjanje amiloid-bete zaista
Dialogue: 0,0:09:13.19,0:09:17.70,Default,,0000,0000,0000,,mnogo brže dok spavamo.
Dialogue: 0,0:09:17.70,0:09:19.38,Default,,0000,0000,0000,,Ukoliko je san
Dialogue: 0,0:09:19.38,0:09:21.34,Default,,0000,0000,0000,,deo načina na koji mozak
Dialogue: 0,0:09:21.34,0:09:23.35,Default,,0000,0000,0000,,rešava uklanjanje otpada,
Dialogue: 0,0:09:23.35,0:09:25.73,Default,,0000,0000,0000,,to bi moglo znatno da promeni način
Dialogue: 0,0:09:25.73,0:09:27.96,Default,,0000,0000,0000,,na koji gledamo odnos između sna,
Dialogue: 0,0:09:27.96,0:09:31.32,Default,,0000,0000,0000,,amiloid-bete i Alchajmerove bolesti.
Dialogue: 0,0:09:31.32,0:09:33.28,Default,,0000,0000,0000,,Niz nedavnih studija pokazuje
Dialogue: 0,0:09:33.28,0:09:35.11,Default,,0000,0000,0000,,da je kod pacijenata
Dialogue: 0,0:09:35.11,0:09:38.20,Default,,0000,0000,0000,,kod kojih se nije sasvim razvila\NAlchajmerova bolest
Dialogue: 0,0:09:38.20,0:09:41.27,Default,,0000,0000,0000,,smanjenje kvaliteta i trajanja sna
Dialogue: 0,0:09:41.27,0:09:43.29,Default,,0000,0000,0000,,povezano sa povećanim nagomilavanjem
Dialogue: 0,0:09:43.29,0:09:46.10,Default,,0000,0000,0000,,amiloid-bete u mozgu.
Dialogue: 0,0:09:46.10,0:09:47.97,Default,,0000,0000,0000,,Važno je napomenuti da
Dialogue: 0,0:09:47.97,0:09:49.68,Default,,0000,0000,0000,,iako ove studije ne dokazuju
Dialogue: 0,0:09:49.68,0:09:51.87,Default,,0000,0000,0000,,da loš san ili njegov nedostatak
Dialogue: 0,0:09:51.87,0:09:54.27,Default,,0000,0000,0000,,izazivaju Alchajmerovu bolest,
Dialogue: 0,0:09:54.27,0:09:56.88,Default,,0000,0000,0000,,ukazuju da nemogućnost mozga
Dialogue: 0,0:09:56.88,0:09:58.80,Default,,0000,0000,0000,,da ukloni otpade
Dialogue: 0,0:09:58.80,0:10:01.55,Default,,0000,0000,0000,,poput amiloid-bete
Dialogue: 0,0:10:01.55,0:10:03.45,Default,,0000,0000,0000,,može da doprinese razvoju
Dialogue: 0,0:10:03.45,0:10:07.07,Default,,0000,0000,0000,,bolesti kao što je Alchajmerova.
Dialogue: 0,0:10:07.07,0:10:08.98,Default,,0000,0000,0000,,Ova istraživanja nam pokazuju
Dialogue: 0,0:10:08.98,0:10:11.30,Default,,0000,0000,0000,,da ono što svi
Dialogue: 0,0:10:11.30,0:10:12.71,Default,,0000,0000,0000,,znamo o snu,
Dialogue: 0,0:10:12.71,0:10:15.36,Default,,0000,0000,0000,,što je i Galen znao,
Dialogue: 0,0:10:15.36,0:10:18.43,Default,,0000,0000,0000,,da sam osvežava i bistri um,
Dialogue: 0,0:10:18.43,0:10:19.98,Default,,0000,0000,0000,,može biti značajan deo
Dialogue: 0,0:10:19.98,0:10:22.29,Default,,0000,0000,0000,,same suštine sna.
Dialogue: 0,0:10:22.29,0:10:23.81,Default,,0000,0000,0000,,Svake noći
Dialogue: 0,0:10:23.81,0:10:25.54,Default,,0000,0000,0000,,ležemo da spavamo,
Dialogue: 0,0:10:25.54,0:10:28.55,Default,,0000,0000,0000,,ali mozak se nikad ne odmara.
Dialogue: 0,0:10:28.55,0:10:30.38,Default,,0000,0000,0000,,Dok je telo nepomično,
Dialogue: 0,0:10:30.38,0:10:33.45,Default,,0000,0000,0000,,a um je negde u zemlji snova,
Dialogue: 0,0:10:33.45,0:10:35.13,Default,,0000,0000,0000,,elegantni mehanizam mozga
Dialogue: 0,0:10:35.13,0:10:37.11,Default,,0000,0000,0000,,neprimetno radi
Dialogue: 0,0:10:37.11,0:10:39.30,Default,,0000,0000,0000,,na čišćenju i održavanju
Dialogue: 0,0:10:39.30,0:10:42.14,Default,,0000,0000,0000,,ove nezamislivo složene mašine.
Dialogue: 0,0:10:42.14,0:10:43.18,Default,,0000,0000,0000,,Poput čišćenja kuće,
Dialogue: 0,0:10:43.18,0:10:45.92,Default,,0000,0000,0000,,to je prljav i nezahvalan posao,
Dialogue: 0,0:10:45.92,0:10:48.18,Default,,0000,0000,0000,,ali i vrlo važan.
Dialogue: 0,0:10:48.18,0:10:50.58,Default,,0000,0000,0000,,Ako mesec dana ne čistite kuhinju
Dialogue: 0,0:10:50.58,0:10:52.49,Default,,0000,0000,0000,,svoje kuće,
Dialogue: 0,0:10:52.49,0:10:54.93,Default,,0000,0000,0000,,veoma brzo u kući neće moći
Dialogue: 0,0:10:54.93,0:10:56.54,Default,,0000,0000,0000,,da se živi.
Dialogue: 0,0:10:56.54,0:10:58.62,Default,,0000,0000,0000,,Što se mozga tiče, posledice
Dialogue: 0,0:10:58.62,0:11:01.56,Default,,0000,0000,0000,,nemara mogu biti mnogo ozbiljnije
Dialogue: 0,0:11:01.56,0:11:04.28,Default,,0000,0000,0000,,od sramote zbog prljavih pultova,
Dialogue: 0,0:11:04.28,0:11:06.85,Default,,0000,0000,0000,,jer je kod čišćenja mozga
Dialogue: 0,0:11:06.85,0:11:09.22,Default,,0000,0000,0000,,u igri samo zdravlje
Dialogue: 0,0:11:09.22,0:11:12.17,Default,,0000,0000,0000,,i rad uma i tela,
Dialogue: 0,0:11:12.17,0:11:14.41,Default,,0000,0000,0000,,i zbog toga je od ključne važnosti
Dialogue: 0,0:11:14.41,0:11:18.68,Default,,0000,0000,0000,,za sprečavanje i lečenje\Nbudućih bolesti uma
Dialogue: 0,0:11:18.68,0:11:21.68,Default,,0000,0000,0000,,razumevanje ovih osnovnih funkcija
Dialogue: 0,0:11:21.68,0:11:24.70,Default,,0000,0000,0000,,održavanja mozga.
Dialogue: 0,0:11:24.70,0:11:26.75,Default,,0000,0000,0000,,Hvala vam.
Dialogue: 0,0:11:26.75,0:11:28.52,Default,,0000,0000,0000,,(Aplauz)