[Script Info]
Title: 
[Events]
Format: Layer, Start, End, Style, Name, MarginL, MarginR, MarginV, Effect, Text
Dialogue: 0,0:00:00.74,0:00:02.38,Default,,0000,0000,0000,,Spavanje.
Dialogue: 0,0:00:02.38,0:00:05.20,Default,,0000,0000,0000,,Trećinu svog života\Nprovedemo spavajući,
Dialogue: 0,0:00:05.20,0:00:08.52,Default,,0000,0000,0000,,ali razumije li itko od nas\No čemu se tu zapravo radi?
Dialogue: 0,0:00:08.52,0:00:10.74,Default,,0000,0000,0000,,Prije dvije tisuće godina Galen,
Dialogue: 0,0:00:10.74,0:00:12.88,Default,,0000,0000,0000,,jedan od najistaknutijih\Nistraživača medicine
Dialogue: 0,0:00:12.88,0:00:13.94,Default,,0000,0000,0000,,starog svijeta,
Dialogue: 0,0:00:13.94,0:00:16.26,Default,,0000,0000,0000,,tvrdio je da dok smo budni,
Dialogue: 0,0:00:16.26,0:00:19.62,Default,,0000,0000,0000,,pokretačka sila našeg mozga,\Nnjegov sok,
Dialogue: 0,0:00:19.62,0:00:22.19,Default,,0000,0000,0000,,prelijeva se u druge dijelove tijela,
Dialogue: 0,0:00:22.19,0:00:26.20,Default,,0000,0000,0000,,oživljavajući ih, ali ujedno\Nostavljajući mozak potpuno osušenim,
Dialogue: 0,0:00:26.20,0:00:27.82,Default,,0000,0000,0000,,i smatrao je da se, kada spavamo,
Dialogue: 0,0:00:27.82,0:00:30.36,Default,,0000,0000,0000,,sva ta vlaga koja je prethodno \Nispunjavala naše tijelo,
Dialogue: 0,0:00:30.36,0:00:32.10,Default,,0000,0000,0000,,vraća natrag,
Dialogue: 0,0:00:32.10,0:00:33.91,Default,,0000,0000,0000,,ponovo hidratizirajući mozak
Dialogue: 0,0:00:33.91,0:00:36.46,Default,,0000,0000,0000,,i osvježavajući um.
Dialogue: 0,0:00:36.46,0:00:38.88,Default,,0000,0000,0000,,Danas nam to zvuči potpuno suludo,
Dialogue: 0,0:00:38.88,0:00:40.92,Default,,0000,0000,0000,,ali Galen je jednostavno pokušao\Nobjasniti
Dialogue: 0,0:00:40.92,0:00:42.53,Default,,0000,0000,0000,,spavanje kao
Dialogue: 0,0:00:42.53,0:00:45.18,Default,,0000,0000,0000,,nešto što radimo svaki dan.
Dialogue: 0,0:00:45.18,0:00:47.11,Default,,0000,0000,0000,,Svi mi iz vlastitog iskustva znamo
Dialogue: 0,0:00:47.11,0:00:49.82,Default,,0000,0000,0000,,da kada spavamo, \Nmozak postaje bistriji,
Dialogue: 0,0:00:49.82,0:00:51.28,Default,,0000,0000,0000,,a kada ne spavamo
Dialogue: 0,0:00:51.28,0:00:54.21,Default,,0000,0000,0000,,mozak postaje mutniji.
Dialogue: 0,0:00:54.21,0:00:56.72,Default,,0000,0000,0000,,Ali unatoč tome što danas\Nznamo mnogo više o spavanju
Dialogue: 0,0:00:56.72,0:00:58.53,Default,,0000,0000,0000,,negoli u Galenovo vrijeme,
Dialogue: 0,0:00:58.53,0:01:01.41,Default,,0000,0000,0000,,još uvijek nismo otkrili \Nzašto baš spavanje,
Dialogue: 0,0:01:01.41,0:01:04.04,Default,,0000,0000,0000,,od svih naših aktivnosti, \Nima ovakvu nevjerojatnu
Dialogue: 0,0:01:04.04,0:01:06.75,Default,,0000,0000,0000,,funkciju obnavljanja uma.
Dialogue: 0,0:01:06.75,0:01:08.25,Default,,0000,0000,0000,,Danas bih vam želio reći\Nnešto više
Dialogue: 0,0:01:08.25,0:01:09.61,Default,,0000,0000,0000,,o nedavnom istraživanju
Dialogue: 0,0:01:09.61,0:01:12.37,Default,,0000,0000,0000,,koje bi moglo razjasniti ovo pitanje.
Dialogue: 0,0:01:12.37,0:01:15.57,Default,,0000,0000,0000,,Otkrili smo da bi spavanje \Nzapravo moglo biti
Dialogue: 0,0:01:15.57,0:01:17.95,Default,,0000,0000,0000,,vrlo elegantno osmišljeno rješenje
Dialogue: 0,0:01:17.95,0:01:20.52,Default,,0000,0000,0000,,za neke od najosnovnijih \Npotreba mozga,
Dialogue: 0,0:01:20.52,0:01:22.47,Default,,0000,0000,0000,,jedinstven način na koji mozak
Dialogue: 0,0:01:22.47,0:01:25.29,Default,,0000,0000,0000,,udovoljava visokim zahtjevima\Ni finesama
Dialogue: 0,0:01:25.29,0:01:30.29,Default,,0000,0000,0000,,koji ga razlikuju od ostalih organa.
Dialogue: 0,0:01:30.29,0:01:33.35,Default,,0000,0000,0000,,Skoro sva biologija koju promatramo
Dialogue: 0,0:01:33.35,0:01:35.80,Default,,0000,0000,0000,,može se promišljati kao\Nniz problema
Dialogue: 0,0:01:35.80,0:01:37.84,Default,,0000,0000,0000,,i niz odgovarajućih rješenja,
Dialogue: 0,0:01:37.84,0:01:41.32,Default,,0000,0000,0000,,a glavni problem koji svaki organ\Nmora riješiti jest
Dialogue: 0,0:01:41.32,0:01:43.82,Default,,0000,0000,0000,,konstantna opskrba svih tih stanica
Dialogue: 0,0:01:43.82,0:01:45.56,Default,,0000,0000,0000,,hranjivim materijalima.
Dialogue: 0,0:01:45.56,0:01:48.14,Default,,0000,0000,0000,,To je posebno važno za mozak;
Dialogue: 0,0:01:48.14,0:01:50.36,Default,,0000,0000,0000,,njegova intenzivna električna aktivnost\Ncrpi
Dialogue: 0,0:01:50.36,0:01:53.21,Default,,0000,0000,0000,,četvrtinu sveukupne energetske\Nzalihe tijela
Dialogue: 0,0:01:53.21,0:01:54.84,Default,,0000,0000,0000,,iako on čini
Dialogue: 0,0:01:54.84,0:01:58.18,Default,,0000,0000,0000,,tek dva posto tjelesne mase.
Dialogue: 0,0:01:58.18,0:01:59.79,Default,,0000,0000,0000,,Krvotok
Dialogue: 0,0:01:59.79,0:02:02.22,Default,,0000,0000,0000,,rješava problem dostave\Nhranjivih tvari
Dialogue: 0,0:02:02.22,0:02:04.76,Default,,0000,0000,0000,,kroz krvne žile koje opskrbljuju \Nhranjivim tvarima
Dialogue: 0,0:02:04.76,0:02:08.11,Default,,0000,0000,0000,,i kisikom svaki djeličak našeg tijela.
Dialogue: 0,0:02:08.11,0:02:11.12,Default,,0000,0000,0000,,Možete to vidjeti u ovom videu.
Dialogue: 0,0:02:11.12,0:02:12.70,Default,,0000,0000,0000,,Ovdje smo snimili krvne žile
Dialogue: 0,0:02:12.70,0:02:15.60,Default,,0000,0000,0000,,u mozgu živog miša.
Dialogue: 0,0:02:15.60,0:02:18.12,Default,,0000,0000,0000,,Krvne žile čine složenu mrežu
Dialogue: 0,0:02:18.12,0:02:20.46,Default,,0000,0000,0000,,koja pokriva cijeli mozak.
Dialogue: 0,0:02:20.46,0:02:22.27,Default,,0000,0000,0000,,Počinju na površini mozga
Dialogue: 0,0:02:22.27,0:02:25.15,Default,,0000,0000,0000,,i zaranjaju u samo tkivo,
Dialogue: 0,0:02:25.15,0:02:27.51,Default,,0000,0000,0000,,i kako se šire, opskrbljuju\Nhranjivim tvarima
Dialogue: 0,0:02:27.51,0:02:33.27,Default,,0000,0000,0000,,i kisikom svaku stanicu \Nu mozgu zasebno.
Dialogue: 0,0:02:33.28,0:02:36.25,Default,,0000,0000,0000,,Kao što svakoj stanici trebaju
Dialogue: 0,0:02:36.25,0:02:38.14,Default,,0000,0000,0000,,hranjive tvari za njen pogon,
Dialogue: 0,0:02:38.14,0:02:41.28,Default,,0000,0000,0000,,tako svaka stanica proizvodi\Notpad kao nusproizvod,
Dialogue: 0,0:02:41.28,0:02:42.82,Default,,0000,0000,0000,,i rješavanje tog otpada
Dialogue: 0,0:02:42.82,0:02:45.09,Default,,0000,0000,0000,,drugi je glavni problem
Dialogue: 0,0:02:45.09,0:02:47.88,Default,,0000,0000,0000,,koji svaki organ mora riješiti.
Dialogue: 0,0:02:47.88,0:02:50.46,Default,,0000,0000,0000,,Ovaj dijagram pokazuje limfni\Nsustav u tijelu
Dialogue: 0,0:02:50.46,0:02:52.90,Default,,0000,0000,0000,,koji se razvio kako bi ispunio\Novu potrebu.
Dialogue: 0,0:02:52.90,0:02:55.71,Default,,0000,0000,0000,,To je druga paralelna mreža žila
Dialogue: 0,0:02:55.71,0:02:57.72,Default,,0000,0000,0000,,koja se širi tijelom.
Dialogue: 0,0:02:57.72,0:02:59.68,Default,,0000,0000,0000,,Uzima proteine i drugi otpad iz
Dialogue: 0,0:02:59.68,0:03:01.60,Default,,0000,0000,0000,,međustaničnog prostora,
Dialogue: 0,0:03:01.60,0:03:04.41,Default,,0000,0000,0000,,skuplja ih i ubacuje u krv
Dialogue: 0,0:03:04.41,0:03:06.68,Default,,0000,0000,0000,,kako bi se oni uklonili.
Dialogue: 0,0:03:06.68,0:03:08.46,Default,,0000,0000,0000,,Ako pažljivije promotrite \N
Dialogue: 0,0:03:08.46,0:03:09.86,Default,,0000,0000,0000,,ovaj dijagram, vidjet ćete nešto
Dialogue: 0,0:03:09.86,0:03:12.19,Default,,0000,0000,0000,,što nema puno smisla.
Dialogue: 0,0:03:12.19,0:03:14.94,Default,,0000,0000,0000,,Ukoliko bismo zumirali \Nglavu ovog čovjeka,
Dialogue: 0,0:03:14.94,0:03:17.14,Default,,0000,0000,0000,,primijetili biste da
Dialogue: 0,0:03:17.14,0:03:21.30,Default,,0000,0000,0000,,u mozgu nema limfnih žila.
Dialogue: 0,0:03:21.30,0:03:24.39,Default,,0000,0000,0000,,Ali to baš i nema previše smisla, zar ne?
Dialogue: 0,0:03:24.39,0:03:27.60,Default,,0000,0000,0000,,Mozak je iznimno aktivan organ
Dialogue: 0,0:03:27.60,0:03:30.16,Default,,0000,0000,0000,,koji proizvodi velike\Nkoličine otpada
Dialogue: 0,0:03:30.16,0:03:32.74,Default,,0000,0000,0000,,kojega se mora učinkovito riješiti.
Dialogue: 0,0:03:32.74,0:03:35.70,Default,,0000,0000,0000,,A opet, tu nema limfnih žila, što znači da
Dialogue: 0,0:03:35.70,0:03:37.50,Default,,0000,0000,0000,,pristup koji ostatak tijela koristi
Dialogue: 0,0:03:37.50,0:03:39.39,Default,,0000,0000,0000,,pri rješavanju otpada,
Dialogue: 0,0:03:39.39,0:03:42.49,Default,,0000,0000,0000,,neće funkcionirati u mozgu.
Dialogue: 0,0:03:42.49,0:03:44.54,Default,,0000,0000,0000,,Pa kako mozak rješava
Dialogue: 0,0:03:44.54,0:03:46.29,Default,,0000,0000,0000,,svoj problem rješavanja otpada?
Dialogue: 0,0:03:46.29,0:03:49.98,Default,,0000,0000,0000,,Upravo je ovo naizgled\Nobično pitanje
Dialogue: 0,0:03:49.98,0:03:53.39,Default,,0000,0000,0000,,navelo našu grupu da se uključi u priču
Dialogue: 0,0:03:53.39,0:03:55.41,Default,,0000,0000,0000,,i otkrili smo,
Dialogue: 0,0:03:55.41,0:03:57.75,Default,,0000,0000,0000,,kad smo zaronili duboko u mozak,
Dialogue: 0,0:03:57.75,0:04:00.64,Default,,0000,0000,0000,,duboko među neurone i krvne žile,
Dialogue: 0,0:04:00.64,0:04:02.82,Default,,0000,0000,0000,,rješenje mozga
Dialogue: 0,0:04:02.82,0:04:05.38,Default,,0000,0000,0000,,za problem rješavanja otpada,
Dialogue: 0,0:04:05.38,0:04:07.20,Default,,0000,0000,0000,,bilo je uistino neočekivano.
Dialogue: 0,0:04:07.20,0:04:10.05,Default,,0000,0000,0000,,Bilo je genijalno,
Dialogue: 0,0:04:10.05,0:04:13.17,Default,,0000,0000,0000,,ali je i lijepo.
Dialogue: 0,0:04:13.17,0:04:14.84,Default,,0000,0000,0000,,Ispričat ću vam što smo pronašli.
Dialogue: 0,0:04:14.84,0:04:17.39,Default,,0000,0000,0000,,Mozak ima veliki bazen
Dialogue: 0,0:04:17.39,0:04:20.85,Default,,0000,0000,0000,,bistre tekućine nazvane \N"cerebrospinalna tekućina".
Dialogue: 0,0:04:20.85,0:04:22.17,Default,,0000,0000,0000,,Mi je zovemo CST.
Dialogue: 0,0:04:22.17,0:04:26.15,Default,,0000,0000,0000,,CST ispunjava prostor koji \Nokružuje mozak,
Dialogue: 0,0:04:26.15,0:04:27.67,Default,,0000,0000,0000,,i otpad iz mozga
Dialogue: 0,0:04:27.67,0:04:29.89,Default,,0000,0000,0000,,izlazi u CST,
Dialogue: 0,0:04:29.89,0:04:33.16,Default,,0000,0000,0000,,koja se s otpadom izbacuje u krv.
Dialogue: 0,0:04:33.16,0:04:34.28,Default,,0000,0000,0000,,Podsjeća na
Dialogue: 0,0:04:34.28,0:04:36.87,Default,,0000,0000,0000,,limfni sustav, zar ne?
Dialogue: 0,0:04:36.87,0:04:39.62,Default,,0000,0000,0000,,Ali zanimjivo je da se\Ntekućina i otpad
Dialogue: 0,0:04:39.62,0:04:41.36,Default,,0000,0000,0000,,iz mozga
Dialogue: 0,0:04:41.36,0:04:43.76,Default,,0000,0000,0000,,ne filtriraju nasumično
Dialogue: 0,0:04:43.76,0:04:46.14,Default,,0000,0000,0000,,u bazene CST, već
Dialogue: 0,0:04:46.14,0:04:49.86,Default,,0000,0000,0000,,postoji vodoinstalacijski sustav
Dialogue: 0,0:04:49.86,0:04:53.75,Default,,0000,0000,0000,,koji organizira i olakšava ovaj proces.
Dialogue: 0,0:04:53.75,0:04:55.90,Default,,0000,0000,0000,,Možete to vidjeti u ovim videima.
Dialogue: 0,0:04:55.90,0:04:58.94,Default,,0000,0000,0000,,Ovdje ponovno skeniramo\Nmozak
Dialogue: 0,0:04:58.94,0:05:00.42,Default,,0000,0000,0000,,živog miša.
Dialogue: 0,0:05:00.42,0:05:02.35,Default,,0000,0000,0000,,Isječak s vaše lijeve strane pokazuje
Dialogue: 0,0:05:02.35,0:05:04.41,Default,,0000,0000,0000,,što se događa na \Npovršini mozga,
Dialogue: 0,0:05:04.41,0:05:05.97,Default,,0000,0000,0000,,a ovaj s desne pokazuje
Dialogue: 0,0:05:05.97,0:05:07.92,Default,,0000,0000,0000,,što se događa ispod površine mozga
Dialogue: 0,0:05:07.92,0:05:09.64,Default,,0000,0000,0000,,unutar samog tkiva.
Dialogue: 0,0:05:09.64,0:05:11.90,Default,,0000,0000,0000,,Označili smo krvne žile crvenom bojom,
Dialogue: 0,0:05:11.90,0:05:13.92,Default,,0000,0000,0000,,a CST koja okružuje mozak
Dialogue: 0,0:05:13.92,0:05:15.74,Default,,0000,0000,0000,,jest zelene boje.
Dialogue: 0,0:05:15.74,0:05:17.54,Default,,0000,0000,0000,,I ono što je nas iznenadilo
Dialogue: 0,0:05:17.54,0:05:20.80,Default,,0000,0000,0000,,jest da tekućina koja se\Nnalazi izvan mozga,
Dialogue: 0,0:05:20.80,0:05:23.61,Default,,0000,0000,0000,,nije ostala vani,
Dialogue: 0,0:05:23.61,0:05:27.01,Default,,0000,0000,0000,,već je CST ispumpana natrag u
Dialogue: 0,0:05:27.01,0:05:28.88,Default,,0000,0000,0000,,i kroz mozak
Dialogue: 0,0:05:28.88,0:05:31.92,Default,,0000,0000,0000,,uz rub krvnih žila.
Dialogue: 0,0:05:31.92,0:05:34.30,Default,,0000,0000,0000,,I dok se tekućina spuštala kroz mozak
Dialogue: 0,0:05:34.30,0:05:36.10,Default,,0000,0000,0000,,uz rubove žila,
Dialogue: 0,0:05:36.10,0:05:38.91,Default,,0000,0000,0000,,pomagala je u čišćenju
Dialogue: 0,0:05:38.91,0:05:41.35,Default,,0000,0000,0000,,otpada iz međustaničnog
Dialogue: 0,0:05:41.35,0:05:44.20,Default,,0000,0000,0000,,prostora mozga.
Dialogue: 0,0:05:44.20,0:05:46.11,Default,,0000,0000,0000,,Ako malo razmislite o tome,
Dialogue: 0,0:05:46.11,0:05:49.59,Default,,0000,0000,0000,,koristeći vanjski rub krvnih žila\Nna ovaj način
Dialogue: 0,0:05:49.59,0:05:52.11,Default,,0000,0000,0000,,zaista je pametno osmišljeno rješenje
Dialogue: 0,0:05:52.11,0:05:54.83,Default,,0000,0000,0000,,jer je mozak zatvoren
Dialogue: 0,0:05:54.83,0:05:56.65,Default,,0000,0000,0000,,unutar tvrde lubanje,
Dialogue: 0,0:05:56.65,0:05:58.76,Default,,0000,0000,0000,,a prepun je stanica,
Dialogue: 0,0:05:58.76,0:06:01.50,Default,,0000,0000,0000,,tako da tu nema viška prostora
Dialogue: 0,0:06:01.50,0:06:05.10,Default,,0000,0000,0000,,za cijeli paralelni sustav žila\Nkao što je limfni sustav.
Dialogue: 0,0:06:05.10,0:06:06.36,Default,,0000,0000,0000,,No krvne žile se ipak
Dialogue: 0,0:06:06.36,0:06:08.32,Default,,0000,0000,0000,,šire od površine mozga
Dialogue: 0,0:06:08.32,0:06:10.93,Default,,0000,0000,0000,,i dopiru do svake stanice u mozgu,
Dialogue: 0,0:06:10.93,0:06:12.16,Default,,0000,0000,0000,,što znači da tekućina
Dialogue: 0,0:06:12.16,0:06:15.46,Default,,0000,0000,0000,,koja putuje uz rub žila
Dialogue: 0,0:06:15.46,0:06:19.26,Default,,0000,0000,0000,,ima lak pristup cijelom mozgu,
Dialogue: 0,0:06:19.26,0:06:21.44,Default,,0000,0000,0000,,pa je to vrlo pametan način
Dialogue: 0,0:06:21.44,0:06:25.21,Default,,0000,0000,0000,,prenamjene jednog sustava žila,\Nkrvnih žila,
Dialogue: 0,0:06:25.21,0:06:27.100,Default,,0000,0000,0000,,kako bi preuzeo i zamijenio funkciju
Dialogue: 0,0:06:27.100,0:06:31.18,Default,,0000,0000,0000,,drugog sustava žila, limfnih žila,
Dialogue: 0,0:06:31.18,0:06:33.59,Default,,0000,0000,0000,,kako ih ne bismo uopće trebali.
Dialogue: 0,0:06:33.59,0:06:35.91,Default,,0000,0000,0000,,Čudesno je to što nijedan \Ndrugi organ
Dialogue: 0,0:06:35.91,0:06:37.55,Default,,0000,0000,0000,,nema ovakav pristup
Dialogue: 0,0:06:37.55,0:06:40.61,Default,,0000,0000,0000,,čišćenju međustaničnog otpada.
Dialogue: 0,0:06:40.61,0:06:46.43,Default,,0000,0000,0000,,To je rješenje karakteristično za mozak,
Dialogue: 0,0:06:46.43,0:06:48.70,Default,,0000,0000,0000,,ali naše otkriće koje nas je \Nnajviše iznenadilo
Dialogue: 0,0:06:48.70,0:06:50.80,Default,,0000,0000,0000,,bilo je da sve ovo,
Dialogue: 0,0:06:50.80,0:06:53.15,Default,,0000,0000,0000,,sve ovo što sam vam ispričao
Dialogue: 0,0:06:53.15,0:06:56.47,Default,,0000,0000,0000,,o tekućini koja ispire mozak,
Dialogue: 0,0:06:56.47,0:07:00.65,Default,,0000,0000,0000,,to se događa samo dok mozak spava.
Dialogue: 0,0:07:00.65,0:07:02.10,Default,,0000,0000,0000,,Ovdje, video s lijeve strane
Dialogue: 0,0:07:02.10,0:07:04.36,Default,,0000,0000,0000,,pokazuje kretanje CST-a
Dialogue: 0,0:07:04.36,0:07:07.97,Default,,0000,0000,0000,,kroz mozak budnog živog miša.
Dialogue: 0,0:07:07.97,0:07:09.84,Default,,0000,0000,0000,,Skoro ništa.
Dialogue: 0,0:07:09.84,0:07:11.42,Default,,0000,0000,0000,,A ipak kod iste životinje,
Dialogue: 0,0:07:11.42,0:07:14.62,Default,,0000,0000,0000,,ako pričekamo samo malo \Ndok ne ode spavati,
Dialogue: 0,0:07:14.62,0:07:17.38,Default,,0000,0000,0000,,vidimo da CST
Dialogue: 0,0:07:17.38,0:07:19.80,Default,,0000,0000,0000,,juri kroz mozak,
Dialogue: 0,0:07:19.80,0:07:21.96,Default,,0000,0000,0000,,a otkrili smo da
Dialogue: 0,0:07:21.96,0:07:24.57,Default,,0000,0000,0000,,kad mozak ide spavati
Dialogue: 0,0:07:24.57,0:07:27.23,Default,,0000,0000,0000,,ujedno se smanjuju moždane stanice
Dialogue: 0,0:07:27.23,0:07:29.27,Default,,0000,0000,0000,,povećavajući prostore između njih
Dialogue: 0,0:07:29.27,0:07:31.41,Default,,0000,0000,0000,,dozvoljavajući tekućini da protekne njima
Dialogue: 0,0:07:31.41,0:07:34.14,Default,,0000,0000,0000,,i tako očisti otpad.
Dialogue: 0,0:07:34.14,0:07:36.65,Default,,0000,0000,0000,,Stoga se čini da je Galen možda čak
Dialogue: 0,0:07:36.65,0:07:38.91,Default,,0000,0000,0000,,bio na pravom tragu pišući o
Dialogue: 0,0:07:38.91,0:07:41.61,Default,,0000,0000,0000,,tekućini koja juri mozgom
Dialogue: 0,0:07:41.61,0:07:43.25,Default,,0000,0000,0000,,kada zaspemo.
Dialogue: 0,0:07:43.25,0:07:46.70,Default,,0000,0000,0000,,Naše istraživanje, 2000 godina kasnije,
Dialogue: 0,0:07:46.70,0:07:48.78,Default,,0000,0000,0000,,pretpostavlja da
Dialogue: 0,0:07:48.78,0:07:50.83,Default,,0000,0000,0000,,mozak u budnom i
Dialogue: 0,0:07:50.83,0:07:52.95,Default,,0000,0000,0000,,najaktivnijem stanju
Dialogue: 0,0:07:52.95,0:07:55.31,Default,,0000,0000,0000,,odgađaa čišćenje otpada
Dialogue: 0,0:07:55.31,0:07:58.38,Default,,0000,0000,0000,,iz međustaničnih prostora za kasnije,
Dialogue: 0,0:07:58.38,0:08:00.24,Default,,0000,0000,0000,,a kada ode spavati
Dialogue: 0,0:08:00.24,0:08:02.59,Default,,0000,0000,0000,,i nije toliko zauzet,
Dialogue: 0,0:08:02.59,0:08:05.16,Default,,0000,0000,0000,,prebacuje se u stanje čišćenja
Dialogue: 0,0:08:05.16,0:08:06.85,Default,,0000,0000,0000,,kako bi očistio otpad
Dialogue: 0,0:08:06.85,0:08:08.36,Default,,0000,0000,0000,,iz međustaničnih prostora,
Dialogue: 0,0:08:08.36,0:08:10.78,Default,,0000,0000,0000,,otpad koji se nakupio tijekom dana.
Dialogue: 0,0:08:10.78,0:08:13.18,Default,,0000,0000,0000,,Na neki je način nalik tome kako vi ili ja
Dialogue: 0,0:08:13.18,0:08:16.27,Default,,0000,0000,0000,,odgađamo kućanske poslove tijekom \Nradnih dana kada se
Dialogue: 0,0:08:16.27,0:08:17.73,Default,,0000,0000,0000,,ne stignemo njima baviti
Dialogue: 0,0:08:17.73,0:08:20.99,Default,,0000,0000,0000,,i onda sve to čišćenje pokušavamo \Nnadoknaditi
Dialogue: 0,0:08:20.99,0:08:23.75,Default,,0000,0000,0000,,preko vikenda.
Dialogue: 0,0:08:23.75,0:08:27.02,Default,,0000,0000,0000,,Puno sam pričao o čišćenju otpada,
Dialogue: 0,0:08:27.02,0:08:28.47,Default,,0000,0000,0000,,ali nisam baš precizno rekao
Dialogue: 0,0:08:28.47,0:08:29.87,Default,,0000,0000,0000,,kakav to otpad
Dialogue: 0,0:08:29.87,0:08:32.16,Default,,0000,0000,0000,,mozak treba očistiti
Dialogue: 0,0:08:32.16,0:08:34.70,Default,,0000,0000,0000,,za vrijeme spavanja kako bi ostao zdrav.
Dialogue: 0,0:08:34.70,0:08:36.30,Default,,0000,0000,0000,,Nusproizvod na koji se nova \N
Dialogue: 0,0:08:36.30,0:08:38.72,Default,,0000,0000,0000,,istraživanja najviše usredotočuju je \Namyloid-beta,
Dialogue: 0,0:08:38.72,0:08:41.91,Default,,0000,0000,0000,,protein koji se u mozgu neprestano stvara.
Dialogue: 0,0:08:41.91,0:08:43.77,Default,,0000,0000,0000,,Moj ga mozak proizvodi upravo sada,
Dialogue: 0,0:08:43.77,0:08:45.93,Default,,0000,0000,0000,,baš kao i vaš.
Dialogue: 0,0:08:45.93,0:08:47.93,Default,,0000,0000,0000,,Ali kod oboljelih od Alzheimera,
Dialogue: 0,0:08:47.93,0:08:50.53,Default,,0000,0000,0000,,amyloid-beta nakuplja se
Dialogue: 0,0:08:50.53,0:08:52.54,Default,,0000,0000,0000,,u prostorima između stanica mozga,
Dialogue: 0,0:08:52.54,0:08:55.97,Default,,0000,0000,0000,,umjesto da se čisti na način na koji \Nbi trebao,
Dialogue: 0,0:08:55.97,0:08:57.98,Default,,0000,0000,0000,,a baš je to nakupljanje amyloid-bete
Dialogue: 0,0:08:57.98,0:09:00.19,Default,,0000,0000,0000,,navodno jedan od ključnih koraka
Dialogue: 0,0:09:00.19,0:09:02.81,Default,,0000,0000,0000,,u razvijanju ove strašne bolesti.
Dialogue: 0,0:09:02.81,0:09:05.91,Default,,0000,0000,0000,,Stoga smo izmjerili koliko se brzo \Namyloid-beta čisti
Dialogue: 0,0:09:05.91,0:09:07.64,Default,,0000,0000,0000,,iz mozga u stanju budnosti
Dialogue: 0,0:09:07.64,0:09:09.42,Default,,0000,0000,0000,,i u stanju spavanja
Dialogue: 0,0:09:09.42,0:09:11.30,Default,,0000,0000,0000,,i otkrili smo da je
Dialogue: 0,0:09:11.30,0:09:13.19,Default,,0000,0000,0000,,čišćenje amyloid-bete
Dialogue: 0,0:09:13.19,0:09:17.70,Default,,0000,0000,0000,,ustinu brže za vrijeme spavanja.
Dialogue: 0,0:09:17.70,0:09:19.38,Default,,0000,0000,0000,,Stoga, ako je spavanje
Dialogue: 0,0:09:19.38,0:09:21.34,Default,,0000,0000,0000,,jedna metoda mozga za
Dialogue: 0,0:09:21.34,0:09:23.35,Default,,0000,0000,0000,,čišćenje otpada,
Dialogue: 0,0:09:23.35,0:09:25.73,Default,,0000,0000,0000,,to može dramatično promijeniti naš način
Dialogue: 0,0:09:25.73,0:09:27.96,Default,,0000,0000,0000,,razmišljanja o odnosu između sna,
Dialogue: 0,0:09:27.96,0:09:31.32,Default,,0000,0000,0000,,amyloid-bete i Alzheimera.
Dialogue: 0,0:09:31.32,0:09:33.28,Default,,0000,0000,0000,,Niz novih kliničkih studija
Dialogue: 0,0:09:33.28,0:09:35.11,Default,,0000,0000,0000,,navodi da kod pacijenata
Dialogue: 0,0:09:35.11,0:09:38.20,Default,,0000,0000,0000,,koji još nisu razvili Alzheimerovu bolest,
Dialogue: 0,0:09:38.20,0:09:41.27,Default,,0000,0000,0000,,pogoršanje u kvaliteti sna i \Nnjegovoj dužini
Dialogue: 0,0:09:41.27,0:09:43.29,Default,,0000,0000,0000,,povezani su s većom količinom
Dialogue: 0,0:09:43.29,0:09:46.10,Default,,0000,0000,0000,,nakupina amyloid-bete u mozgu,
Dialogue: 0,0:09:46.10,0:09:47.97,Default,,0000,0000,0000,,i iako je važno napomenuti
Dialogue: 0,0:09:47.97,0:09:49.68,Default,,0000,0000,0000,,da ove studije ne dokazuju
Dialogue: 0,0:09:49.68,0:09:51.87,Default,,0000,0000,0000,,da manjak sna ili loš san
Dialogue: 0,0:09:51.87,0:09:54.27,Default,,0000,0000,0000,,uzrokuju Alzheimerovu bolest,
Dialogue: 0,0:09:54.27,0:09:56.88,Default,,0000,0000,0000,,one sugeriraju da nemogućnost mozga
Dialogue: 0,0:09:56.88,0:09:58.80,Default,,0000,0000,0000,,da održi svoj životni prostor čistim,
Dialogue: 0,0:09:58.80,0:10:01.55,Default,,0000,0000,0000,,čisteći ga od otpada poput amyloid-bete,
Dialogue: 0,0:10:01.55,0:10:03.45,Default,,0000,0000,0000,,može doprinijeti razvitku
Dialogue: 0,0:10:03.45,0:10:07.07,Default,,0000,0000,0000,,poremećaja poput Alzheimera.
Dialogue: 0,0:10:07.07,0:10:08.98,Default,,0000,0000,0000,,Ovo novo israživanje govori nam
Dialogue: 0,0:10:08.98,0:10:11.30,Default,,0000,0000,0000,,da bi sve ono što smo svi mi
Dialogue: 0,0:10:11.30,0:10:12.71,Default,,0000,0000,0000,,već znali o spavanju,
Dialogue: 0,0:10:12.71,0:10:15.36,Default,,0000,0000,0000,,ono što je čak i Galen shvaćao,
Dialogue: 0,0:10:15.36,0:10:18.43,Default,,0000,0000,0000,,da ono osvježava i pročišćava um,
Dialogue: 0,0:10:18.43,0:10:19.98,Default,,0000,0000,0000,,mogao biti glavni
Dialogue: 0,0:10:19.98,0:10:22.29,Default,,0000,0000,0000,,razlog postojanja sna.
Dialogue: 0,0:10:22.29,0:10:23.81,Default,,0000,0000,0000,,Vi i ja idemo spavati
Dialogue: 0,0:10:23.81,0:10:25.54,Default,,0000,0000,0000,,svake noći,
Dialogue: 0,0:10:25.54,0:10:28.55,Default,,0000,0000,0000,,ali naši mozgovi nikad ne odmaraju.
Dialogue: 0,0:10:28.55,0:10:30.38,Default,,0000,0000,0000,,Dok je naše tijelo u mirovanju,
Dialogue: 0,0:10:30.38,0:10:33.45,Default,,0000,0000,0000,,a naš um šeće po snovima,
Dialogue: 0,0:10:33.45,0:10:35.13,Default,,0000,0000,0000,,mozak kao uglađen stroj
Dialogue: 0,0:10:35.13,0:10:37.11,Default,,0000,0000,0000,,tiho, ali naporno
Dialogue: 0,0:10:37.11,0:10:39.30,Default,,0000,0000,0000,,čisti i održava
Dialogue: 0,0:10:39.30,0:10:42.14,Default,,0000,0000,0000,,taj nezamislivo kompleksni stroj.
Dialogue: 0,0:10:42.14,0:10:43.18,Default,,0000,0000,0000,,Poput kućanskih poslova,
Dialogue: 0,0:10:43.18,0:10:45.92,Default,,0000,0000,0000,,to je prljav i nezahvalan posao,
Dialogue: 0,0:10:45.92,0:10:48.18,Default,,0000,0000,0000,,ali je i važan posao.
Dialogue: 0,0:10:48.18,0:10:50.72,Default,,0000,0000,0000,,Ako prestanemo čistiti
Dialogue: 0,0:10:50.72,0:10:52.49,Default,,0000,0000,0000,,kuhinju na mjesec dana,
Dialogue: 0,0:10:52.49,0:10:54.93,Default,,0000,0000,0000,,naš će cijeli dom vrlo brzo postati
Dialogue: 0,0:10:54.93,0:10:56.54,Default,,0000,0000,0000,,neprikladan za život.
Dialogue: 0,0:10:56.54,0:10:58.62,Default,,0000,0000,0000,,U mozgu posljedice
Dialogue: 0,0:10:58.62,0:11:01.56,Default,,0000,0000,0000,,odgađanja čišćenja mogu biti mnogo veće
Dialogue: 0,0:11:01.56,0:11:04.28,Default,,0000,0000,0000,,od neugode koju će kod nas izazvati \Nprljavi šankovi
Dialogue: 0,0:11:04.28,0:11:06.85,Default,,0000,0000,0000,,jer kad se radi o čišćenju mozga,
Dialogue: 0,0:11:06.85,0:11:09.22,Default,,0000,0000,0000,,tada je na kocki zdravlje i funkcija
Dialogue: 0,0:11:09.22,0:11:10.95,Default,,0000,0000,0000,,uma i tijela
Dialogue: 0,0:11:12.68,0:11:14.41,Default,,0000,0000,0000,,i zato je ključno danas razumjeti
Dialogue: 0,0:11:14.41,0:11:18.68,Default,,0000,0000,0000,,ove osnovne održavajuće funkcije mozga
Dialogue: 0,0:11:18.68,0:11:21.68,Default,,0000,0000,0000,,koje bi mogle biti ključne u prevenciji \Ni liječenju
Dialogue: 0,0:11:21.68,0:11:24.70,Default,,0000,0000,0000,,bolesti uma sutra.
Dialogue: 0,0:11:24.70,0:11:26.75,Default,,0000,0000,0000,,Hvala vam!
Dialogue: 0,0:11:26.75,0:11:28.52,Default,,0000,0000,0000,,(Pljesak. )