[Script Info]
Title: 
[Events]
Format: Layer, Start, End, Style, Name, MarginL, MarginR, MarginV, Effect, Text
Dialogue: 0,0:00:00.09,0:00:03.10,Default,,0000,0000,0000,,well
Dialogue: 0,0:00:03.10,0:00:06.48,Default,,0000,0000,0000,,well it was you know as
Dialogue: 0,0:00:07.34,0:00:11.59,Default,,0000,0000,0000,,typical have really interesting\Ndevelopment in that
Dialogue: 0,0:00:11.06,0:00:14.15,Default,,0000,0000,0000,,I was looking for something else and and\Nyou know it was that
Dialogue: 0,0:00:15.05,0:00:18.11,Default,,0000,0000,0000,,it was a like PCR with the
Dialogue: 0,0:00:19.00,0:00:23.02,Default,,0000,0000,0000,,the possible the the outcome other\Nsolution
Dialogue: 0,0:00:23.02,0:00:27.02,Default,,0000,0000,0000,,to hypothetical problem that did not\Nexist and I was working on
Dialogue: 0,0:00:27.02,0:00:30.80,Default,,0000,0000,0000,,trying to sequence single base-pair
Dialogue: 0,0:00:31.03,0:00:35.63,Default,,0000,0000,0000,,you know then whether call snips today\Nsingle nucleotide polymorphism
Dialogue: 0,0:00:35.06,0:00:39.08,Default,,0000,0000,0000,,with because those were medically\Nimportant now is trying
Dialogue: 0,0:00:39.65,0:00:43.19,Default,,0000,0000,0000,,to do it with oligonucleotides because\NIran
Dialogue: 0,0:00:43.02,0:00:46.02,Default,,0000,0000,0000,,a lab that made them and we had
Dialogue: 0,0:00:46.02,0:00:50.03,Default,,0000,0000,0000,,really improve the efficiency with which\Nwe made them earn
Dialogue: 0,0:00:50.03,0:00:53.60,Default,,0000,0000,0000,,the three or four years prior said
Dialogue: 0,0:00:53.83,0:00:56.83,Default,,0000,0000,0000,,we're making we can make mine faster\Nthan the company's
Dialogue: 0,0:00:57.33,0:01:01.75,Default,,0000,0000,0000,,cedars I word for could use them had\Nseven people working for me
Dialogue: 0,0:01:01.08,0:01:06.13,Default,,0000,0000,0000,,and I was thinking on you have to cut\Nstep down to like about three kids now
Dialogue: 0,0:01:07.03,0:01:09.05,Default,,0000,0000,0000,,we get the salon omitted devices
Dialogue: 0,0:01:09.05,0:01:12.11,Default,,0000,0000,0000,,on tonight arm into increase the demand
Dialogue: 0,0:01:13.01,0:01:16.04,Default,,0000,0000,0000,,for all you can eat I'm so sorry think\Nyou know what else can you do with them
Dialogue: 0,0:01:16.04,0:01:19.14,Default,,0000,0000,0000,,and that it's possible to make if
Dialogue: 0,0:01:20.00,0:01:23.61,Default,,0000,0000,0000,,a rapid clinical and safer single
Dialogue: 0,0:01:24.01,0:01:27.63,Default,,0000,0000,0000,,his polymorphism like sickle cell anemia
Dialogue: 0,0:01:27.06,0:01:30.16,Default,,0000,0000,0000,,was a good example people there that
Dialogue: 0,0:01:30.73,0:01:35.81,Default,,0000,0000,0000,,back then maybe you going ok Lanigan you\Ntake a sample maybe three weeks later
Dialogue: 0,0:01:36.58,0:01:39.60,Default,,0000,0000,0000,,you know which is monitor agonizing
Dialogue: 0,0:01:39.83,0:01:43.59,Default,,0000,0000,0000,,other you be nice to have been one shift\Nhospital
Dialogue: 0,0:01:43.06,0:01:46.27,Default,,0000,0000,0000,,in you and that let you know and I
Dialogue: 0,0:01:46.80,0:01:50.24,Default,,0000,0000,0000,,I thought oligonucleotides maybe with\Nthe answer there were that
Dialogue: 0,0:01:50.02,0:01:53.03,Default,,0000,0000,0000,,I was really home add as
Dialogue: 0,0:01:53.05,0:01:56.12,Default,,0000,0000,0000,,other chemists I still make him and
Dialogue: 0,0:01:57.02,0:02:01.10,Default,,0000,0000,0000,,I really didn't have an appreciation for\Nhappy huge dance
Dialogue: 0,0:02:01.33,0:02:05.00,Default,,0000,0000,0000,,human genome compared to say five\Nthousand base pair
Dialogue: 0,0:02:05.00,0:02:09.00,Default,,0000,0000,0000,,plasma that I was using isn't serb model\Nsystem
Dialogue: 0,0:02:09.00,0:02:13.08,Default,,0000,0000,0000,,and and I was was thinking this method
Dialogue: 0,0:02:13.01,0:02:17.78,Default,,0000,0000,0000,,require couple organically times wanna\Nmiss Serbia control what they would be
Dialogue: 0,0:02:18.57,0:02:19.43,Default,,0000,0000,0000,,pointed
Dialogue: 0,0:02:19.04,0:02:22.12,Default,,0000,0000,0000,,right toward each other just like in PCR\Nreaction and
Dialogue: 0,0:02:23.02,0:02:26.03,Default,,0000,0000,0000,,and then I and I was thinking I mean it\Nreally love
Dialogue: 0,0:02:26.03,0:02:29.07,Default,,0000,0000,0000,,pics sexe nucleotide triphosphates
Dialogue: 0,0:02:29.07,0:02:32.14,Default,,0000,0000,0000,,mind there's a couple technical problems\Ntrying to solve in 10 min
Dialogue: 0,0:02:33.00,0:02:37.02,Default,,0000,0000,0000,,a the whales in and decide to solve it\Nwas to
Dialogue: 0,0:02:37.06,0:02:40.41,Default,,0000,0000,0000,,use to like run a sort of sham reaction
Dialogue: 0,0:02:40.96,0:02:45.02,Default,,0000,0000,0000,,first with the oligonucleotides in place\Nin the sample
Dialogue: 0,0:02:45.52,0:02:50.39,Default,,0000,0000,0000,,and then and then I had my break\Nactresses and suffering and again
Dialogue: 0,0:02:50.04,0:02:53.09,Default,,0000,0000,0000,,and because he was going to use a it is
Dialogue: 0,0:02:53.09,0:02:56.28,Default,,0000,0000,0000,,not for two not the idea and for the\Nfight
Dialogue: 0,0:02:57.10,0:03:01.15,Default,,0000,0000,0000,,duplicating the signal but then I\Nrealized the side effect to that was
Dialogue: 0,0:03:01.63,0:03:02.98,Default,,0000,0000,0000,,going to be the house pointed
Dialogue: 0,0:03:02.10,0:03:05.10,Default,,0000,0000,0000,,double the the signal if
Dialogue: 0,0:03:05.10,0:03:09.19,Default,,0000,0000,0000,,there were enough like the exit Euclid\Nhas available are trying to get readers
Dialogue: 0,0:03:10.09,0:03:12.17,Default,,0000,0000,0000,,if there are any come in with the same
Dialogue: 0,0:03:13.02,0:03:16.10,Default,,0000,0000,0000,,that you are driving a man was right he\Ndoes not have this in your head you
Dialogue: 0,0:03:16.85,0:03:17.56,Default,,0000,0000,0000,,thinking about
Dialogue: 0,0:03:17.06,0:03:20.08,Default,,0000,0000,0000,,constantly in and it just realized that\Nthere is a way the
Dialogue: 0,0:03:20.08,0:03:24.41,Default,,0000,0000,0000,,you don't think in the lab as much you\Nknow I do you think
Dialogue: 0,0:03:25.16,0:03:29.92,Default,,0000,0000,0000,,I was spending my weekends opinion this\Nin a little cabin
Dialogue: 0,0:03:29.09,0:03:32.49,Default,,0000,0000,0000,,and I Drive up every Friday night income\Na concern
Dialogue: 0,0:03:33.32,0:03:37.04,Default,,0000,0000,0000,,and that's really all the nice things\Nbut to a half hours
Dialogue: 0,0:03:37.00,0:03:40.06,Default,,0000,0000,0000,,and e sorry your
Dialogue: 0,0:03:40.06,0:03:44.15,Default,,0000,0000,0000,,uydess got some new to me and you can't\Ndo anything else
Dialogue: 0,0:03:45.05,0:03:48.07,Default,,0000,0000,0000,,to think as this when I did most to my\Nthinking
Dialogue: 0,0:03:48.07,0:03:51.12,Default,,0000,0000,0000,,usually his the day-to-day life in a\Nlaboratory
Dialogue: 0,0:03:52.00,0:03:55.29,Default,,0000,0000,0000,,doesn't allow alive now
Dialogue: 0,0:03:55.49,0:03:59.95,Default,,0000,0000,0000,,with all these letters in your inbox and\Nuse your phone ringing in his own these
Dialogue: 0,0:03:59.10,0:04:01.02,Default,,0000,0000,0000,,people have to deal with and 70 have
Dialogue: 0,0:04:01.88,0:04:07.90,Default,,0000,0000,0000,,really that kind I'm
Dialogue: 0,0:04:08.07,0:04:09.77,Default,,0000,0000,0000,,I'll
Dialogue: 0,0:04:09.08,0:04:09.10,Default,,0000,0000,0000,,of