0:00:06.855,0:00:12.955 In the savannahs of Kenya, two female [br]northern white rhinos, Nájin and Fatu, 0:00:12.955,0:00:15.565 munch contentedly on the grass. 0:00:15.565,0:00:18.040 At the time of this video’s publication, 0:00:18.040,0:00:23.390 these are the last two known [br]northern white rhinos left on Earth. 0:00:23.390,0:00:26.030 Their species is functionally extinct— 0:00:26.030,0:00:29.990 without a male, [br]Nájin and Fatu can’t reproduce. 0:00:29.990,0:00:34.410 And yet, there’s still hope to revive [br]the northern white rhino. 0:00:34.410,0:00:36.269 How can that be? 0:00:36.269,0:00:38.700 The story starts about 50 years ago, 0:00:38.700,0:00:42.330 when poachers began illegally hunting [br]thousands of rhinos 0:00:42.330,0:00:45.340 across Africa for their horns. 0:00:45.340,0:00:48.440 This, combined with civil wars [br]in their territory, 0:00:48.440,0:00:51.640 decimated northern white rhino [br]populations. 0:00:51.640,0:00:57.427 Concerned conservationists began trying [br]to breed them in captivity in the 1970s, 0:00:57.427,0:01:00.707 collecting and storing semen from males. 0:01:00.707,0:01:05.474 Only four rhinos were ultimately born [br]through the ambitious breeding program. 0:01:05.474,0:01:09.824 Nájin, and her daughter Fatu [br]were the last two. 0:01:09.824,0:01:15.440 In 2014, conservationists discovered [br]that neither can have a calf. 0:01:15.440,0:01:19.530 Though Nájin gave birth to Fatu, [br]she now has weak hindlegs, 0:01:19.530,0:01:23.437 which could harm her health [br]if she became pregnant again. 0:01:23.437,0:01:27.128 Fatu, meanwhile, [br]has a degenerated uterine lining. 0:01:27.128,0:01:34.112 Then, the last northern white rhino male [br]of the species, Sudan, died in 2018. 0:01:34.112,0:01:38.062 But there was one glimmer of hope: [br]artificial reproduction. 0:01:38.062,0:01:42.539 With no living males and no females [br]able to carry a pregnancy, 0:01:42.539,0:01:46.531 this is a complicated and risky process [br]to say the least. 0:01:46.531,0:01:51.125 Though scientists had stored semen, [br]they would have to collect the eggs— 0:01:51.125,0:01:56.759 a complex procedure that requires a female[br]to be sedated for up to two hours. 0:01:56.759,0:02:00.419 Then, they’d create a viable embryo [br]in the lab— 0:02:00.419,0:02:05.150 something that had never been done before,[br]and no one knew how to do. 0:02:05.150,0:02:06.980 Even that was just the beginning— 0:02:06.980,0:02:10.341 a surrogate mother [br]of another rhino species 0:02:10.341,0:02:13.272 would have to carry the embryo to term. 0:02:13.272,0:02:17.422 Females of a closely related species, [br]the southern white rhino, 0:02:17.422,0:02:21.092 became both the key to developing [br]a rhino embryo in a lab 0:02:21.092,0:02:25.062 and the leading candidates [br]for surrogate mothers. 0:02:25.062,0:02:29.552 Northern and southern white rhinos [br]diverged about a million of years ago 0:02:29.552,0:02:33.542 into separate— though still [br]closely-related— species. 0:02:33.542,0:02:38.038 They inhabit different regions, and have [br]slightly different physical traits. 0:02:38.038,0:02:42.108 In a fortunate coincidence, [br]several female southern white rhinos 0:02:42.108,0:02:45.042 needed treatment [br]for their own reproductive problems, 0:02:45.042,0:02:49.412 and researchers could collect eggs [br]as part of that treatment. 0:02:49.412,0:02:53.427 In Dvůr Králové Zoo in October 2015, 0:02:53.427,0:02:59.111 experts of IZW Berlin began collecting [br]eggs from southern white rhinos 0:02:59.111,0:03:04.895 and sending them to Avantea, an animal [br]reproduction laboratory in Italy. 0:03:04.895,0:03:11.921 There, scientists developed and perfected [br]a technique to create a viable embryo. 0:03:11.921,0:03:13.651 Once they mastered the technique, 0:03:13.651,0:03:19.709 researchers extracted Nájin and Fatu’s [br]eggs on August 22, 2019 0:03:19.709,0:03:21.769 and flew them to Italy. 0:03:21.769,0:03:25.187 Three days later, they fertilized [br]the eggs with sperm 0:03:25.187,0:03:27.737 from a northern white rhino male. 0:03:27.737,0:03:32.029 After another week, two of the eggs [br]made it to the stage of development 0:03:32.029,0:03:36.111 when the embryo can be frozen [br]and preserved for future. 0:03:36.111,0:03:41.049 Another collection in December 2019 [br]produced one more embryo. 0:03:41.049,0:03:47.919 As of early 2020, the plan is to collect [br]Nájin and Fatu’s eggs three times a year 0:03:47.919,0:03:49.809 if they’re healthy enough. 0:03:49.809,0:03:51.999 In the meantime, [br]researchers are looking for 0:03:51.999,0:03:55.179 promising southern white rhino [br]surrogate mothers— 0:03:55.179,0:03:58.979 ideally who’ve carried a pregnancy [br]to term before. 0:03:58.979,0:04:02.289 The surrogacy plan [br]is somewhat of a leap of faith— 0:04:02.289,0:04:05.209 southern and northern white rhinos [br]have interbred 0:04:05.209,0:04:10.149 both during the last glacial period [br]and more recently in 1977, 0:04:10.149,0:04:13.859 so researchers are optimistic [br]a southern white rhino 0:04:13.859,0:04:17.109 would be able to carry [br]a northern white rhino to term. 0:04:17.109,0:04:20.909 Also, the two species’ pregnancies [br]are the same length. 0:04:20.909,0:04:24.879 Still, transferring an embryo [br]to a rhino is tricky 0:04:24.879,0:04:27.179 because of the shape of the cervix. 0:04:27.179,0:04:29.809 The ultimate goal, [br]which will take decades, 0:04:29.809,0:04:34.249 is to establish a breeding population [br]of northern white rhinos 0:04:34.249,0:04:36.577 in their original range. 0:04:36.577,0:04:39.769 Studies suggest that we have samples [br]from enough individuals 0:04:39.769,0:04:45.420 to recreate a population with the genetic [br]diversity the species had a century ago. 0:04:45.420,0:04:47.890 Though the specifics [br]of this effort are unique, 0:04:47.890,0:04:52.146 as more species face critical endangerment[br]or functional extinction, 0:04:52.146,0:04:55.529 it’s also an arena for big questions: 0:04:55.529,0:04:59.846 do we have a responsibility to try [br]to bring species back from the brink, 0:04:59.846,0:05:03.928 especially when human actions [br]brought them there in the first place? 0:05:03.928,0:05:06.724 Are there limits to the effort [br]we should expend 0:05:06.724,0:05:10.196 on saving animals threatened [br]with extinction?