0:00:10.025,0:00:11.111 Oh the humanity! 0:00:13.730,0:00:15.651 Ah... humanity... 0:00:16.210,0:00:19.162 It’s a trainwreck,[br]but I can’t look away. 0:00:20.206,0:00:23.576 It’s 1843, and a debate is raging [br]among physicians 0:00:23.576,0:00:28.089 about one of the most common [br]killers of women: childbed fever. 0:00:28.089,0:00:31.569 Childbed fever strikes [br]within days of giving birth, 0:00:31.569,0:00:37.983 killing more than 70% of those infected—[br]and nobody knows what causes it. 0:00:37.983,0:00:41.846 Obstetrician Charles Meigs has a theory. 0:00:41.846,0:00:43.928 Having observed abdominal inflammation 0:00:43.928,0:00:46.498 in patients who go on [br]to develop the fever, 0:00:46.498,0:00:51.114 he claims this inflammation [br]is the cause of childbed fever. 0:00:51.114,0:00:54.954 Much of the medical establishment[br]supports his theory. 0:00:54.954,0:00:56.424 Oh, come on! 0:00:56.424,0:01:01.114 They really leave me no choice [br]but to teach them some skepticism. 0:01:12.891,0:01:13.959 That’s better. 0:01:14.871,0:01:21.687 Now, Meigs, your argument is based [br]on a fallacy— the false cause fallacy. 0:01:21.687,0:01:25.687 Correlation does not imply causation: 0:01:25.687,0:01:28.927 When two phenomena regularly occur[br]together, 0:01:28.927,0:01:33.725 one does not necessarily [br]cause the other. 0:01:33.725,0:01:39.666 So you say women who have inflammation[br]also come down with childbed fever, 0:01:39.666,0:01:43.666 therefore the inflammation [br]caused the fever. 0:01:43.666,0:01:46.966 But that’s not necessarily true. 0:01:46.966,0:01:51.116 Yes, yes, the inflammation comes first,[br]then the fever, 0:01:51.116,0:01:55.116 so it seems like the inflammation [br]causes the fever. 0:01:55.116,0:02:00.400 But by that logic, since babies [br]usually grow hair before teeth, 0:02:00.400,0:02:03.630 hair growth must cause tooth growth. 0:02:03.630,0:02:06.460 And we all know that’s not true,[br]right? 0:02:06.460,0:02:08.280 Actually, don’t answer that. 0:02:08.280,0:02:11.991 A couple of different things [br]could be going on here. 0:02:11.991,0:02:16.668 First, it’s possible that fever [br]and inflammation are correlated 0:02:16.668,0:02:19.588 purely by coincidence. 0:02:19.588,0:02:25.627 Or, there could be a causal relationship[br]that’s the opposite of what you think— 0:02:25.627,0:02:28.627 the fever causes the inflammation, 0:02:28.627,0:02:31.747 rather than the inflammation [br]causing the fever. 0:02:31.747,0:02:38.535 Or both could share a common [br]underlying cause you haven’t thought of. 0:02:38.535,0:02:46.059 If I may, just what do you think [br]causes inflammation? Nothing? 0:02:46.059,0:02:49.519 It just is? Really? 0:02:49.519,0:02:54.257 Humor me for a moment in discussing[br]one of your colleague’s ideas— 0:02:54.257,0:02:56.847 Dr. Oliver Wendell Holmes. 0:02:56.847,0:03:00.157 I know, I know, [br]you don’t like his theory— 0:03:00.157,0:03:03.377 you already wrote [br]a scathing letter about it. 0:03:03.377,0:03:06.477 But let’s fill your students in, shall we? 0:03:06.477,0:03:12.289 Holmes noticed a pattern: [br]when a patient dies of childbed fever, 0:03:12.289,0:03:15.199 a doctor performs an autopsy. 0:03:15.199,0:03:18.599 If the doctor then treats a new patient, 0:03:18.599,0:03:22.599 that patient often comes [br]down with the fever. 0:03:22.599,0:03:24.094 Based on this correlation 0:03:24.094,0:03:29.384 between autopsies of fever victims[br]and new fever patients, 0:03:29.384,0:03:32.150 he proposes a possible cause. 0:03:32.150,0:03:38.705 Since there’s no evidence that the autopsy[br]causes the fever beyond this correlation, 0:03:38.705,0:03:43.774 he doesn’t jump to the conclusion [br]that autopsy causes fever. 0:03:43.774,0:03:49.230 Instead, he suggests that doctors [br]are infecting their patients 0:03:49.230,0:03:54.922 via an invisible contaminant [br]on their hands and surgical instruments. 0:03:54.922,0:04:00.750 This idea outrages most doctors, [br]who see themselves as infallible. 0:04:00.750,0:04:04.880 Like Meigs here, who refuses [br]to consider the possibility 0:04:04.880,0:04:08.440 that he’s playing a role [br]in his patients’ plight. 0:04:08.440,0:04:13.523 His flawed argument doesn’t leave any [br]path forward for further investigation— 0:04:13.523,0:04:15.743 but Holmes’ does. 0:04:24.222,0:04:27.492 It’s 1847, and physician Ignaz Semmelweis 0:04:27.492,0:04:29.752 has reduced the number [br]of childbed fever deaths 0:04:29.752,0:04:34.832 in a clinic from 12% to 1% [br]by requiring all medical personnel 0:04:34.832,0:04:40.162 to disinfect their hands after autopsies[br]and between patient examinations. 0:04:40.162,0:04:45.252 With this initiative, he has proven[br]the contagious nature of childbed fever. 0:04:45.552,0:04:46.692 Ha! 0:04:50.368,0:04:53.845 It’s 1879, and Louis Pasteur [br]has identified 0:04:53.845,0:04:58.371 the contaminant responsible [br]for many cases of childbed fever: 0:04:58.371,0:05:01.411 Hemolytic streptococcus bacteria. 0:05:04.301,0:05:07.151 Hmm, my fries are cold. 0:05:07.151,0:05:10.501 Must be because my ice cream melted.